| Comparative genomics reveals adaptive evolution of asian tapeworm in switching to a new intermediate host | |
| Wang, Shuai1; Wang, Sen2,3; Luo, Yingfeng2; Xiao, Lihua4; Luo, Xuenong1; Gao, Shenghan2; Dou, Yongxi1; Zhang, Huangkai2,3; Guo, Aijiang1; Meng, Qingshu2 | |
| 刊名 | Nature communications
 |
| 2016-09-01 | |
| 卷号 | 7页码:10 |
| ISSN号 | 2041-1723 |
| DOI | 10.1038/ncomms12845 |
| 通讯作者 | Zhu, guan(gzhu@cvm.tamu.edu) ; Hu, songnian(husn@big.ac.cn) ; Cai, xuepeng(caixuepeng@caas.cn) |
| 英文摘要 | Taenia saginata, taenia solium and taenia asiatica (beef, pork and asian tapeworms, respectively) are parasitic flatworms of major public health and food safety importance. among them, t. asiatica is a newly recognized species that split from t. saginata via an intermediate host switch similar to 1.14 myr ago. here we report the 169- and 168-mb draft genomes of t. saginata and t. asiatica. comparative analysis reveals that high rates of gene duplications and functional diversifications might have partially driven the divergence between t. asiatica and t. saginata. we observe accelerated evolutionary rates, adaptive evolutions in homeostasis regulation, tegument maintenance and lipid uptakes, and differential/specialized gene family expansions in t. asiatica that may favour its hepatotropism in the new intermediate host. we also identify potential targets for developing diagnostic or intervention tools against human tapeworms. these data provide new insights into the evolution of taenia parasites, particularly the recent speciation of t. asiatica. |
| WOS关键词 | ECHINOCOCCUS-GRANULOSUS ; TAENIA-ASIATICA ; MAXIMUM-LIKELIHOOD ; GENE DUPLICATION ; MODERN HUMANS ; ANTIGEN-B ; ALIGNMENT ; PARASITE ; SEQUENCE ; ORIGINS |
| WOS研究方向 | Science & Technology - Other Topics |
| WOS类目 | Multidisciplinary Sciences |
| 语种 | 英语 |
| 出版者 | NATURE PUBLISHING GROUP |
| WOS记录号 | WOS:000385363000013 |
| 内容类型 | 期刊论文 |
| URI标识 | http://www.corc.org.cn/handle/1471x/2374861 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Zhu, Guan; Hu, Songnian; Cai, Xuepeng |
| 作者单位 | 1.Chinese Acad Agr Sci, Lanzhou Vet Res Inst, Key Lab Vet Parasitol Gansu Prov, State Key Lab Vet Etiol Biol, Lanzhou 730046, Gansu, Peoples R China 2.Chinese Acad Sci, CAS Key Lab Genome Sci & Informat, Beijing Inst Genom, Beijing 100101, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Ctr Dis Control & Prevent, Div Foodborne Waterborne & Environm Dis, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA 30329 USA 5.Chinese Acad Sci, Core Genom Facil, Beijing Inst Genom, Beijing 100101, Peoples R China 6.Texas A&M Univ, Coll Vet Med & Biomed Sci, Dept Vet Pathobiol, College Stn, TX 77843 USA |
| 推荐引用方式 GB/T 7714 | Wang, Shuai,Wang, Sen,Luo, Yingfeng,et al. Comparative genomics reveals adaptive evolution of asian tapeworm in switching to a new intermediate host[J]. Nature communications,2016,7:10. |
| APA | Wang, Shuai.,Wang, Sen.,Luo, Yingfeng.,Xiao, Lihua.,Luo, Xuenong.,...&Cai, Xuepeng.(2016).Comparative genomics reveals adaptive evolution of asian tapeworm in switching to a new intermediate host.Nature communications,7,10. |
| MLA | Wang, Shuai,et al."Comparative genomics reveals adaptive evolution of asian tapeworm in switching to a new intermediate host".Nature communications 7(2016):10. |
| 个性服务 |
| 查看访问统计 |
| 相关权益政策 |
| 暂无数据 |
| 收藏/分享 |
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
修改评论