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Super-resolution imaging in glycoscience: new developments and challenges
Chen, Junling1,2; Tong, Ti3; Wang, Hongda1
刊名Journal of innovative optical health sciences
2016-05-01
卷号9期号:3页码:16
关键词Carbohydrate Super-resolution imaging
ISSN号1793-5458
DOI10.1142/s179354581630007x
通讯作者Tong, ti(tti666@163.com)
英文摘要Carbohydrates on cell surfaces play a crucial role in a wide variety of biological processes, including cell adhesion, recognition and signaling, viral and bacterial infection, inflammation and metastasis. however, owing to the large diversity and complexity of carbohydrate structure and nongenetically synthesis, glycoscience is the least understood field compared with genomics and proteomics. although the structures and functions of carbohydrates have been investigated by various conventional analysis methods, the distribution and role of carbohydrates in cell membranes remain elusive. this review focuses on the developments and challenges of super-resolution imaging in glycoscience through introduction of imaging principle and the available fluorescent probes for super-resolution imaging, the labeling strategies of carbohydrates, and the recent applications of super-resolution imaging in glycoscience, which will promote the super-resolution imaging technology as a promising tool to provide new insights into the study of glycoscience.
WOS关键词OPTICAL RECONSTRUCTION MICROSCOPY ; IN-VITRO SELECTION ; PHOTOACTIVATED LOCALIZATION MICROSCOPY ; MOLECULE-FORCE SPECTROSCOPY ; O-LINKED GLYCOSYLATION ; TENTACLE TYPE PEPTIDES ; CELL-SURFACE GLYCANS ; FLUORESCENT-PROBES ; LIVE-CELL ; ARTIFICIAL LECTINS
WOS研究方向Optics ; Radiology, Nuclear Medicine & Medical Imaging
WOS类目Optics ; Radiology, Nuclear Medicine & Medical Imaging
语种英语
出版者WORLD SCIENTIFIC PUBL CO PTE LTD
WOS记录号WOS:000379752700003
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/2374574
专题中国科学院大学
通讯作者Tong, Ti
作者单位1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Jilin, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Jilin Univ, Hosp 2, Dept Thorac Surg, Changchun 130041, Jilin, Peoples R China
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GB/T 7714
Chen, Junling,Tong, Ti,Wang, Hongda. Super-resolution imaging in glycoscience: new developments and challenges[J]. Journal of innovative optical health sciences,2016,9(3):16.
APA Chen, Junling,Tong, Ti,&Wang, Hongda.(2016).Super-resolution imaging in glycoscience: new developments and challenges.Journal of innovative optical health sciences,9(3),16.
MLA Chen, Junling,et al."Super-resolution imaging in glycoscience: new developments and challenges".Journal of innovative optical health sciences 9.3(2016):16.
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