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Pgaweb: a web server for bacterial pan-genome analysis
Chen, Xinyu1; Zhang, Yadong2,3,4; Zhang, Zhewen2,3; Zhao, Yongbing5; Sun, Chen6; Yang, Ming7; Wang, Jinyue2,3,4; Liu, Qian1,8; Zhang, Baohua1,8; Chen, Meili2,3
刊名Frontiers in microbiology
2018-08-21
卷号9页码:8
关键词Web server Bacterial pan-genome analysis Genome dynamics visualization Genome structure interpretation Orthologous gene identification
ISSN号1664-302X
DOI10.3389/fmicb.2018.01910
通讯作者Jin, zhong(zjin@sccas.cn) ; Xiao, jingfa(xiaojngfa@big.ac.cn)
英文摘要An astronomical increase in microbial genome data in recent years has led to strong demand for bioinformatic tools for pan-genome analysis within and across species. here, we present pgaweb, a user-friendly, web-based tool for bacterial pan-genome analysis, which is composed of two main pan-genome analysis modules, pgap and pgap-x. pgaweb provides key interactive and customizable functions that include orthologous clustering, pan-genome profiling, sequence variation and evolution analysis, and functional classification. pgaweb presents features of genomic structural dynamics and sequence diversity with different visualization methods that are helpful for intuitively understanding the dynamics and evolution of bacterial genomes. pgaweb has an intuitive interface with one-click setting of parameters and is freely available at http://pgaweb.vlcc.cn/.
WOS关键词TOOL ; ORTHOLOGS
WOS研究方向Microbiology
WOS类目Microbiology
语种英语
出版者FRONTIERS MEDIA SA
WOS记录号WOS:000442210500001
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/2374278
专题计算机网络信息中心
通讯作者Jin, Zhong; Xiao, Jingfa
作者单位1.Chinese Acad Sci, Comp Network Informat Ctr, Beijing, Peoples R China
2.Chinese Acad Sci, BIG Data Ctr, Beijing Inst Genom, Beijing, Peoples R China
3.Chinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genome Sci & Informat, Beijing, Peoples R China
4.Univ Chinese Acad Sci, Coll Life Sci, Beijing, Peoples R China
5.NIAMSD, Lymphocyte Nucl Biol, NIH, Bethesda, MD 20892 USA
6.Penn State Univ, Dept Comp Sci & Engn, University Pk, PA 16802 USA
7.Chinese Acad Sci, Off Gen Affairs, Beijing, Peoples R China
8.Chinese Acad Sci, Ctr Sci Comp Applicat & Res, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Chen, Xinyu,Zhang, Yadong,Zhang, Zhewen,et al. Pgaweb: a web server for bacterial pan-genome analysis[J]. Frontiers in microbiology,2018,9:8.
APA Chen, Xinyu.,Zhang, Yadong.,Zhang, Zhewen.,Zhao, Yongbing.,Sun, Chen.,...&Xiao, Jingfa.(2018).Pgaweb: a web server for bacterial pan-genome analysis.Frontiers in microbiology,9,8.
MLA Chen, Xinyu,et al."Pgaweb: a web server for bacterial pan-genome analysis".Frontiers in microbiology 9(2018):8.
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