QQ客服 官方微博 反馈留言

	Aluminum nanoparticles enhance anticancer immune response induced by tumor cell vaccine
	Sun,Zhao1; Wang,Wei2; Wang,Rui3; Duan,Jinhong2; Hu,Yan2; Ma,Jin2; Zhou,Jiayan2; Xie,Sishen4; Lu,Xin1; Zhu,Zhaohui1
刊名	Cancer nanotechnology
	2010-05-07
卷号	1期号:1-6
关键词	Aluminum Nanoparticle Anticancer Immune adjuvant
ISSN号	1868-6958
DOI	10.1007/s12645-010-0001-5
通讯作者	Xu,haiyan(xuhy@pumc.edu.cn) ; Wang,chen(wangch@iccas.ac.cn) ; Yang,xian-da(ayangmd@gmail.com)
英文摘要	Abstractthe application of nanomaterial in cancer treatment is promising and intriguing. anti-tumor immunotherapy has the potential to significantly improve the prognosis of cancer treatment, though the efficacy of immunotherapy generally needs further improvement. one way to improve the efficacy is using immune adjuvants, but the adjuvants for anticancer immunotherapy have to be more potent than for prophylactic vaccines. here, we report that compared to conventional alum adjuvant, aluminum oxide nanoparticles (nano-alum) may further enhance the anticancer effects of an immunotherapy that employs tumor cell vaccine (tcv). the average tumor size tends to be lower in animals that receive the combinational treatment of nano-alum and tcv. the anticancer cytotoxicity by the lymphocytes was also significantly higher in the treatment group that received both tcv and nano-alum. these results suggest that nano-alum may potentially serve as a potent immune adjuvant and have prospective applications in anticancer immunotherapy.
语种	英语
出版者	Springer Vienna
WOS记录号	BMC:10.1007/S12645-010-0001-5
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2373545
专题	物理研究所
通讯作者	Xu,Haiyan; Wang,Chen; Yang,Xian-Da
作者单位	1.Peking Union Medical College Hospital 2.Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences 3.National Center of Nanoscience and Technology 4.Institute of Physics, Chinese Academy of Sciences 5.Beijing TianTan Hospital
推荐引用方式 GB/T 7714	Sun,Zhao,Wang,Wei,Wang,Rui,et al. Aluminum nanoparticles enhance anticancer immune response induced by tumor cell vaccine[J]. Cancer nanotechnology,2010,1(1-6).
APA	Sun,Zhao.,Wang,Wei.,Wang,Rui.,Duan,Jinhong.,Hu,Yan.,...&Yang,Xian-Da.(2010).Aluminum nanoparticles enhance anticancer immune response induced by tumor cell vaccine.Cancer nanotechnology,1(1-6).
MLA	Sun,Zhao,et al."Aluminum nanoparticles enhance anticancer immune response induced by tumor cell vaccine".Cancer nanotechnology 1.1-6(2010).

个性服务

查看访问统计

相关权益政策

暂无数据

收藏/分享

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。