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Cell-imprinted polydimethylsiloxane for the selective cell adhesion
Liu, Lukuan1,2,3; Yang, Kaiguang2; Dai, Zhongpeng2; Liang, Zhen2; Zhang, Lihua2; Peng, Xiaojun1; Zhang, Yukui2
刊名Chinese chemical letters
2019-03-01
卷号30期号:3页码:672-675
关键词Cell adhesion Aptamer Cell imprinting Hierarchical structures Click chemistry
ISSN号1001-8417
DOI10.1016/j.cclet.2018.11.006
通讯作者Zhang, lihua(lihuazhang@dicp.ac.cn)
英文摘要Cell adhesion is the basis for some cell isolation methods, and is influenced by both of the biochemical and topographic characteristics of the substrates. herein, based on cell imprinting and click chemistry, we have developed a cell-imprinted polydimethylsiloxane (pdms) with aptamer functionalization (apt-cis). the atom force microscopic analysis results showed that the hierarchical structure matching well with the target cells is successfully introduced on the surface of the apt-cis. by using the synergistic effects of hierarchical structure and aptamer affinity, the apt-cis was successfully used for the selective cell adhesion, and 93.9% +/- 0.8% of the captured cells could then be released. thus, the apt-cis holds promise in selective cell isolation and sorting fields. (c) 2018 chinese chemical society and institute of materia medica, chinese academy of medical sciences. published by elsevier b.v. all rights reserved.
WOS关键词CANCER-CELLS ; APTAMER ; RECOGNITION ; CAPTURE
WOS研究方向Chemistry
WOS类目Chemistry, Multidisciplinary
语种英语
出版者ELSEVIER SCIENCE INC
WOS记录号WOS:000462106900031
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/2372645
专题大连化学物理研究所
通讯作者Zhang, Lihua
作者单位1.Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Liu, Lukuan,Yang, Kaiguang,Dai, Zhongpeng,et al. Cell-imprinted polydimethylsiloxane for the selective cell adhesion[J]. Chinese chemical letters,2019,30(3):672-675.
APA Liu, Lukuan.,Yang, Kaiguang.,Dai, Zhongpeng.,Liang, Zhen.,Zhang, Lihua.,...&Zhang, Yukui.(2019).Cell-imprinted polydimethylsiloxane for the selective cell adhesion.Chinese chemical letters,30(3),672-675.
MLA Liu, Lukuan,et al."Cell-imprinted polydimethylsiloxane for the selective cell adhesion".Chinese chemical letters 30.3(2019):672-675.
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