Cell-imprinted polydimethylsiloxane for the selective cell adhesion | |
Liu, Lukuan1,2,3; Yang, Kaiguang2; Dai, Zhongpeng2; Liang, Zhen2; Zhang, Lihua2; Peng, Xiaojun1; Zhang, Yukui2 | |
刊名 | Chinese chemical letters
![]() |
2019-03-01 | |
卷号 | 30期号:3页码:672-675 |
关键词 | Cell adhesion Aptamer Cell imprinting Hierarchical structures Click chemistry |
ISSN号 | 1001-8417 |
DOI | 10.1016/j.cclet.2018.11.006 |
通讯作者 | Zhang, lihua(lihuazhang@dicp.ac.cn) |
英文摘要 | Cell adhesion is the basis for some cell isolation methods, and is influenced by both of the biochemical and topographic characteristics of the substrates. herein, based on cell imprinting and click chemistry, we have developed a cell-imprinted polydimethylsiloxane (pdms) with aptamer functionalization (apt-cis). the atom force microscopic analysis results showed that the hierarchical structure matching well with the target cells is successfully introduced on the surface of the apt-cis. by using the synergistic effects of hierarchical structure and aptamer affinity, the apt-cis was successfully used for the selective cell adhesion, and 93.9% +/- 0.8% of the captured cells could then be released. thus, the apt-cis holds promise in selective cell isolation and sorting fields. (c) 2018 chinese chemical society and institute of materia medica, chinese academy of medical sciences. published by elsevier b.v. all rights reserved. |
WOS关键词 | CANCER-CELLS ; APTAMER ; RECOGNITION ; CAPTURE |
WOS研究方向 | Chemistry |
WOS类目 | Chemistry, Multidisciplinary |
语种 | 英语 |
出版者 | ELSEVIER SCIENCE INC |
WOS记录号 | WOS:000462106900031 |
内容类型 | 期刊论文 |
URI标识 | http://www.corc.org.cn/handle/1471x/2372645 |
专题 | 大连化学物理研究所 |
通讯作者 | Zhang, Lihua |
作者单位 | 1.Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Liu, Lukuan,Yang, Kaiguang,Dai, Zhongpeng,et al. Cell-imprinted polydimethylsiloxane for the selective cell adhesion[J]. Chinese chemical letters,2019,30(3):672-675. |
APA | Liu, Lukuan.,Yang, Kaiguang.,Dai, Zhongpeng.,Liang, Zhen.,Zhang, Lihua.,...&Zhang, Yukui.(2019).Cell-imprinted polydimethylsiloxane for the selective cell adhesion.Chinese chemical letters,30(3),672-675. |
MLA | Liu, Lukuan,et al."Cell-imprinted polydimethylsiloxane for the selective cell adhesion".Chinese chemical letters 30.3(2019):672-675. |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论