Synthesized phosphorylated and aminated derivatives of fucoidan and their potential antioxidant activity in vitro

doi:10.1016/j.ijbiomac.2008.11.010

	Synthesized phosphorylated and aminated derivatives of fucoidan and their potential antioxidant activity in vitro
	Wang, Jing1,2 ; Zhang, Quanbin 1; Zhang, Zhongshan 1,2; Zhang, Jingjing 1,2; Li, Pengcheng1
刊名	INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
	2009-03-01
卷号	44 期号:2 页码:170-174
关键词	Fucoidan Phosphorylated Aminated Antioxidant Activity
ISSN号	0141-8130
DOI	10.1016/j.ijbiomac.2008.11.010
文献子类	Article
英文摘要	Three sulfated polysaccharide derivatives (phosphorylated and aminated fucoidan) were synthesized, and their potential antioxidant activities were investigated employing various established in vitro systems. Two methods were used in phosphorylation fucoidan: polyphosphoric acid and POCl(3) method. Aminated fucoidan was prepared using the epichlorohydrin and ammonia water. All fucoidan derivatives possessed considerable antioxidant activity, and exhibited stronger antioxidant ability than fucoidan in certain tests. The phosphorylated fucoidan showed stronger hydroxyl radical and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and reducing power. The mechanism on influence the antioxidant activity of samples of phosphate and amino group was indicated. (C) 2008 Elsevier B.V. All rights reserved.; Three sulfated polysaccharide derivatives (phosphorylated and aminated fucoidan) were synthesized, and their potential antioxidant activities were investigated employing various established in vitro systems. Two methods were used in phosphorylation fucoidan: polyphosphoric acid and POCl3 method. Aminated fucoidan was prepared using the epichlorohydrin and ammonia water. All fucoidan derivatives possessed considerable antioxidant activity, and exhibited stronger antioxidant ability than fucoidan in certain tests. The phosphorylated fucoidan showed stronger hydroxyl radical and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and reducing power. The mechanism on influence the antioxidant activity of samples of phosphate and amino group was indicated. (C) 2008 Elsevier B.V. All rights reserved.
学科主题	Biochemistry & Molecular Biology
URL标识	查看原文
语种	英语
WOS记录号	WOS:000263927000009
公开日期	2010-12-22
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/3497]
专题	海洋研究所_海洋生物技术研发中心
作者单位	1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Wang, Jing,Zhang, Quanbin,Zhang, Zhongshan,et al. Synthesized phosphorylated and aminated derivatives of fucoidan and their potential antioxidant activity in vitro[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2009,44(2):170-174.
APA	Wang, Jing,Zhang, Quanbin,Zhang, Zhongshan,Zhang, Jingjing,&Li, Pengcheng.(2009).Synthesized phosphorylated and aminated derivatives of fucoidan and their potential antioxidant activity in vitro.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,44(2),170-174.
MLA	Wang, Jing,et al."Synthesized phosphorylated and aminated derivatives of fucoidan and their potential antioxidant activity in vitro".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 44.2(2009):170-174.