Studies of iridoid glycosides using liquid chromatography/electrospray ionization tandem mass spectrometry

	Studies of iridoid glycosides using liquid chromatography/electrospray ionization tandem mass spectrometry
	Ren, Lingling; Xue, Xingya; Zhang, Feifang; Wang, Yongcan; Liu, Yanfang; Li, Cunman; Liang, Xinmiao
刊名	rapid communications in mass spectrometry
	2007
卷号	21 期号:18 页码:3039-3050
通讯作者	梁鑫淼
产权排序	1;1
英文摘要	fragmentation pathways of five iridoid glycosides have been studied by using electrospray ionization multi-stage tandem mass spectrometry (esi-msn). the first-stage ms data of the five iridoid glycosides were compared. the ms spectra showed that the adduct ions of iridoid glycosides and the formate anion were diagnostic ions to distinguish iridoid glycosides with a carboxyl group at the c-4 position or an ester group at the c-4 position. the ms fragmentation pathways of the five iridoid glycosides were also studied. analyzing the product ion spectra of iridoid glycosides, some neutral losses were observed, such as h2o, co2 and glucose residues, which were very useful for the identification of the functional groups in the structures of iridoid glycosides. furthermore, specific loss of one molecule of methyl 3-oxopropanoate or 3-oxopropanic acid was firstly discussed, which corresponded to the isomerization of the hemiacetal group in the structure of iridoid aglycone. according to the fragmentation mechanisms and hplc/msn data, the structures of five iridoid glycosides in a crude extract of gardenia jasminoisdes fruit have been identified. three compounds were compared with standards and the other two were identified as shanzhiside and genipin gentibioside by their msn data without standard compounds. in order to further validate the veracity of the deduction, genipin gentiobioside was isolated from the extract of gardenia jasminoisdes fruit using purification factory and was further identified by c- and h-nmr. copyright (c) 2007 john wiley & sons, ltd.
WOS标题词	science & technology ; physical sciences ; technology
类目[WOS]	chemistry, analytical ; spectroscopy
研究领域[WOS]	chemistry ; spectroscopy
关键词[WOS]	collision-induced dissociation ; electrokinetic capillary chromatography ; electrospray-ionization ; gardenia-jasminoides ; geniposide ; identification ; glucosides ; fruit ; acid
收录类别	SCI
原文出处	true
语种	英语
WOS记录号	WOS:000249457800016
公开日期	2010-11-30
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/99807]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Ren, Lingling,Xue, Xingya,Zhang, Feifang,et al. Studies of iridoid glycosides using liquid chromatography/electrospray ionization tandem mass spectrometry[J]. rapid communications in mass spectrometry,2007,21(18):3039-3050.
APA	Ren, Lingling.,Xue, Xingya.,Zhang, Feifang.,Wang, Yongcan.,Liu, Yanfang.,...&Liang, Xinmiao.(2007).Studies of iridoid glycosides using liquid chromatography/electrospray ionization tandem mass spectrometry.rapid communications in mass spectrometry,21(18),3039-3050.
MLA	Ren, Lingling,et al."Studies of iridoid glycosides using liquid chromatography/electrospray ionization tandem mass spectrometry".rapid communications in mass spectrometry 21.18(2007):3039-3050.