Lipophilic marine toxins discovered in the Bohai Sea using high performance liquid chromatography coupled with tandem mass spectrometry

doi:10.1016/j.chemosphere.2017.05.073

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	Lipophilic marine toxins discovered in the Bohai Sea using high performance liquid chromatography coupled with tandem mass spectrometry
	Liu, Yang1,2 ; Yu, Ren-Cheng 1,2,3; Kong, Fan-Zhou1,3 ; Li, Chen 4; Dai, Li 1,2; Chen, Zhen-Fan 1,2; Zhou, Ming-Jiang 1
刊名	CHEMOSPHERE
	2017-09-01
卷号	183 页码:380-388
关键词	High Performance Liquid Chromatography-tandem Mass Spectrometry (Hplc-ms/ms) The Bohai Sea Lipophilic Marine Toxins Phytoplankton
DOI	10.1016/j.chemosphere.2017.05.073
文献子类	Article
英文摘要	Some dinoflagellates can produce lipophilic marine toxins, which pose potent threats to seafood consumers. In the Bohai Sea, an important semi-closed inland sea with intensive mariculture industry in China, there is little knowledge concerning lipophilic marine toxins and their potential threats. In this study, net-concentrated phytoplankton samples were periodically collected from 5 typical mariculture zones around the Bohai Sea, including Laishan (LS), Laizhou (LZ), Hangu (HG), Qinhuangdao (QHD) and Huludao (HLD) in 2013 and 2014, and a method using high performance liquid chromatography (HPLC) coupled with a Q-Trap mass spectrometer was applied to analyze seven representative lipophilic marine toxins, including okadaic acid (OA), dinophysistoxin-1 (DTX1), pectenotoxin-2 (PTX2), yessotoxin (YTX), azaspiracid-1 (AZA1), gymnodimine (GYM), and 13-desmethyl spirolide C (desMeC). The method had high sensitivity and repeatability, and exhibited satisfactory recoveries for most of the lipophilic marine toxins (92.1-108%) except for AZA1 (65.8-68.9%). Nearly all the lipophilic marine toxins could be detected in phytoplankton samples from the Bohai Sea. OA, DTX1 and PTX2 were predominant components and present in most of the phytoplankton samples. The maximum content of lipophilic marine toxin in phytoplankton samples concentrated from seawater (OA 464 pg L-1; DTX1 783 pg L-1; YTX 86.6 pg L-1; desMeC 15.6 pg L-1; PTX2 1.11 x 10(3) pg L-1) appeared in June 2014. Based on toxins present in phytoplankton samples, it is implied that seafood in the Bohai Sea is more likely to be contaminated by OA group and PTX group toxins, and spring is the high-risk season for toxin contamination. (C) 2017 Elsevier Ltd. All rights reserved.
语种	英语
WOS记录号	WOS:000404196400042
内容类型	期刊论文
版本	出版稿
源URL	[http://ir.qdio.ac.cn/handle/337002/137116]
专题	海洋研究所_海洋生态与环境科学重点实验室
作者单位	1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 4.Chinese Acad Sci, Inst Oceanol, Res Ctr Anal & Measurement, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Liu, Yang,Yu, Ren-Cheng,Kong, Fan-Zhou,et al. Lipophilic marine toxins discovered in the Bohai Sea using high performance liquid chromatography coupled with tandem mass spectrometry[J]. CHEMOSPHERE,2017,183:380-388.
APA	Liu, Yang.,Yu, Ren-Cheng.,Kong, Fan-Zhou.,Li, Chen.,Dai, Li.,...&Zhou, Ming-Jiang.(2017).Lipophilic marine toxins discovered in the Bohai Sea using high performance liquid chromatography coupled with tandem mass spectrometry.CHEMOSPHERE,183,380-388.
MLA	Liu, Yang,et al."Lipophilic marine toxins discovered in the Bohai Sea using high performance liquid chromatography coupled with tandem mass spectrometry".CHEMOSPHERE 183(2017):380-388.