Isolation, antimicrobial activity, and metabolites of fungus Cladosporium sp associated with red alga Porphyra yezoensis

doi:10.1007/s00284-007-9063-y

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	Isolation, antimicrobial activity, and metabolites of fungus Cladosporium sp associated with red alga Porphyra yezoensis
	Ding, Ling 1,2; Qin, Song 1; Li, Fuchao 1; Chi, Xiaoyuan 1; Laatsch, Hartmut 3
刊名	CURRENT MICROBIOLOGY
	2008-03-01
卷号	56 期号:3 页码:229-235
关键词	Antifungal Activity Causative Organism Pythium-porphyrae Phenylacetic Acid Rot Disease Marine Substances Surfaces Strain
ISSN号	0343-8651
DOI	10.1007/s00284-007-9063-y
文献子类	Article
英文摘要	Cladosporium sp. isolate N5 was isolated as a dominant fungus from the healthy conchocelis of Porphyra yezoensis. In the re-infection test, it did not cause any pathogenic symptoms in the alga. Twenty-one cultural conditions were chosen to test its antimicrobial activity in order to obtain the best condition for large-scale fermentation. Phenylacetic acid, p-hydroxyphenylethyl alcohol, and L-beta-phenyllactic acid were isolated from the crude extract as strong antimicrobial compounds and they are the first reported secondary metabolites for the genus Cladosporium. In addition, the Cladosporium sp. produced the reported Porphyra yezoensis growth regulators phenylacetic acid and p-hydroxyphenylacetic acid. No cytotoxicity was found in the brine shrimp lethality test, which indicated that the environmental-friendly Cladosporium sp. could be used as a potential biocontrol agent to protect the alga from pathogens.; Cladosporium sp. isolate N5 was isolated as a dominant fungus from the healthy conchocelis of Porphyra yezoensis. In the re-infection test, it did not cause any pathogenic symptoms in the alga. Twenty-one cultural conditions were chosen to test its antimicrobial activity in order to obtain the best condition for large-scale fermentation. Phenylacetic acid, p-hydroxyphenylethyl alcohol, and L-beta-phenyllactic acid were isolated from the crude extract as strong antimicrobial compounds and they are the first reported secondary metabolites for the genus Cladosporium. In addition, the Cladosporium sp. produced the reported Porphyra yezoensis growth regulators phenylacetic acid and p-hydroxyphenylacetic acid. No cytotoxicity was found in the brine shrimp lethality test, which indicated that the environmental-friendly Cladosporium sp. could be used as a potential biocontrol agent to protect the alga from pathogens.
学科主题	Microbiology
URL标识	查看原文
语种	英语
WOS记录号	WOS:000252975000006
公开日期	2010-12-24
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/5537]
专题	海洋研究所_实验海洋生物学重点实验室
作者单位	1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Univ Gottingen, Dept Organ & Biomol Chem, D-37077 Gottingen, Germany
推荐引用方式 GB/T 7714	Ding, Ling,Qin, Song,Li, Fuchao,et al. Isolation, antimicrobial activity, and metabolites of fungus Cladosporium sp associated with red alga Porphyra yezoensis[J]. CURRENT MICROBIOLOGY,2008,56(3):229-235.
APA	Ding, Ling,Qin, Song,Li, Fuchao,Chi, Xiaoyuan,&Laatsch, Hartmut.(2008).Isolation, antimicrobial activity, and metabolites of fungus Cladosporium sp associated with red alga Porphyra yezoensis.CURRENT MICROBIOLOGY,56(3),229-235.
MLA	Ding, Ling,et al."Isolation, antimicrobial activity, and metabolites of fungus Cladosporium sp associated with red alga Porphyra yezoensis".CURRENT MICROBIOLOGY 56.3(2008):229-235.