Bromophenols from the marine red alga Polysiphonia urceolata with DPPH radical scavenging activity
Li, Ke1,2; Li, Xiao-Ming1; Ji, Nai-Yun1,2; Wang, Bin-Gui1; Wang, BG, Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China
刊名JOURNAL OF NATURAL PRODUCTS
2008
卷号71期号:1页码:28-30
关键词Symphyocladia-latiuscula Rhodomela-confervoides Derivatives Fractions
ISSN号0163-3864
DOI10.1021/np070281p
文献子类Article
英文摘要Three new (1-3) and three known (4-6) bromophenols were isolated and identified from the marine red alga Polysiphonia urceolata. On the basis of extensive analysis of spectroscopic data, the structures of these compounds were determined to be 7-bromo-9,10-dihydrophenanthrene-2,3,5,6-tetraol (1), 4,7-dibromo-9,10-dihydrophenanthrene-2,3,5,6-tetraol (2), 1,8-dibromo-5,7-dihydrodibenzo[c,e]oxepine-2,3,9,10-tetraol (3), urceolatol (4), 3-,bromo-4,5-dihydroxybenzaidehyde (5), and 3,5-dibromo-4-hydroxybenzaldehyde (6). Each of the isolated compounds was evaluated for alpha,alpha-dipheny1-beta-picrylhydrazyl (DPPH) radical scavenging activity, and all were found to be potent, with IC50 values ranging from 6.1 to 35.8 mu M, compared to the positive control, butylated hydroxytoluene (BHT), with an IC50 of 83.8 mu M.; Three new (1-3) and three known (4-6) bromophenols were isolated and identified from the marine red alga Polysiphonia urceolata. On the basis of extensive analysis of spectroscopic data, the structures of these compounds were determined to be 7-bromo-9,10-dihydrophenanthrene-2,3,5,6-tetraol (1), 4,7-dibromo-9,10-dihydrophenanthrene-2,3,5,6-tetraol (2), 1,8-dibromo-5,7-dihydrodibenzo[c,e]oxepine-2,3,9,10-tetraol (3), urceolatol (4), 3-,bromo-4,5-dihydroxybenzaidehyde (5), and 3,5-dibromo-4-hydroxybenzaldehyde (6). Each of the isolated compounds was evaluated for alpha,alpha-dipheny1-beta-picrylhydrazyl (DPPH) radical scavenging activity, and all were found to be potent, with IC50 values ranging from 6.1 to 35.8 mu M, compared to the positive control, butylated hydroxytoluene (BHT), with an IC50 of 83.8 mu M.
学科主题Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
URL标识查看原文
语种英语
WOS记录号WOS:000252629400007
公开日期2010-11-18
内容类型期刊论文
源URL[http://ir.qdio.ac.cn/handle/337002/1638]  
专题海洋研究所_实验海洋生物学重点实验室
通讯作者Wang, BG, Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China
作者单位1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Li, Ke,Li, Xiao-Ming,Ji, Nai-Yun,et al. Bromophenols from the marine red alga Polysiphonia urceolata with DPPH radical scavenging activity[J]. JOURNAL OF NATURAL PRODUCTS,2008,71(1):28-30.
APA Li, Ke,Li, Xiao-Ming,Ji, Nai-Yun,Wang, Bin-Gui,&Wang, BG, Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China.(2008).Bromophenols from the marine red alga Polysiphonia urceolata with DPPH radical scavenging activity.JOURNAL OF NATURAL PRODUCTS,71(1),28-30.
MLA Li, Ke,et al."Bromophenols from the marine red alga Polysiphonia urceolata with DPPH radical scavenging activity".JOURNAL OF NATURAL PRODUCTS 71.1(2008):28-30.
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