Bromophenols from the marine red alga Polysiphonia urceolata with DPPH radical scavenging activity | |
Li, Ke1,2; Li, Xiao-Ming1; Ji, Nai-Yun1,2; Wang, Bin-Gui1![]() | |
刊名 | JOURNAL OF NATURAL PRODUCTS
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2008 | |
卷号 | 71期号:1页码:28-30 |
关键词 | Symphyocladia-latiuscula Rhodomela-confervoides Derivatives Fractions |
ISSN号 | 0163-3864 |
DOI | 10.1021/np070281p |
文献子类 | Article |
英文摘要 | Three new (1-3) and three known (4-6) bromophenols were isolated and identified from the marine red alga Polysiphonia urceolata. On the basis of extensive analysis of spectroscopic data, the structures of these compounds were determined to be 7-bromo-9,10-dihydrophenanthrene-2,3,5,6-tetraol (1), 4,7-dibromo-9,10-dihydrophenanthrene-2,3,5,6-tetraol (2), 1,8-dibromo-5,7-dihydrodibenzo[c,e]oxepine-2,3,9,10-tetraol (3), urceolatol (4), 3-,bromo-4,5-dihydroxybenzaidehyde (5), and 3,5-dibromo-4-hydroxybenzaldehyde (6). Each of the isolated compounds was evaluated for alpha,alpha-dipheny1-beta-picrylhydrazyl (DPPH) radical scavenging activity, and all were found to be potent, with IC50 values ranging from 6.1 to 35.8 mu M, compared to the positive control, butylated hydroxytoluene (BHT), with an IC50 of 83.8 mu M.; Three new (1-3) and three known (4-6) bromophenols were isolated and identified from the marine red alga Polysiphonia urceolata. On the basis of extensive analysis of spectroscopic data, the structures of these compounds were determined to be 7-bromo-9,10-dihydrophenanthrene-2,3,5,6-tetraol (1), 4,7-dibromo-9,10-dihydrophenanthrene-2,3,5,6-tetraol (2), 1,8-dibromo-5,7-dihydrodibenzo[c,e]oxepine-2,3,9,10-tetraol (3), urceolatol (4), 3-,bromo-4,5-dihydroxybenzaidehyde (5), and 3,5-dibromo-4-hydroxybenzaldehyde (6). Each of the isolated compounds was evaluated for alpha,alpha-dipheny1-beta-picrylhydrazyl (DPPH) radical scavenging activity, and all were found to be potent, with IC50 values ranging from 6.1 to 35.8 mu M, compared to the positive control, butylated hydroxytoluene (BHT), with an IC50 of 83.8 mu M. |
学科主题 | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
URL标识 | 查看原文 |
语种 | 英语 |
WOS记录号 | WOS:000252629400007 |
公开日期 | 2010-11-18 |
内容类型 | 期刊论文 |
源URL | [http://ir.qdio.ac.cn/handle/337002/1638] ![]() |
专题 | 海洋研究所_实验海洋生物学重点实验室 |
通讯作者 | Wang, BG, Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China |
作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Li, Ke,Li, Xiao-Ming,Ji, Nai-Yun,et al. Bromophenols from the marine red alga Polysiphonia urceolata with DPPH radical scavenging activity[J]. JOURNAL OF NATURAL PRODUCTS,2008,71(1):28-30. |
APA | Li, Ke,Li, Xiao-Ming,Ji, Nai-Yun,Wang, Bin-Gui,&Wang, BG, Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China.(2008).Bromophenols from the marine red alga Polysiphonia urceolata with DPPH radical scavenging activity.JOURNAL OF NATURAL PRODUCTS,71(1),28-30. |
MLA | Li, Ke,et al."Bromophenols from the marine red alga Polysiphonia urceolata with DPPH radical scavenging activity".JOURNAL OF NATURAL PRODUCTS 71.1(2008):28-30. |
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