New Cytotoxic Cycloartane Triterpenes from the Aerial Parts of Actaea heracleifolia (syn. Cimicifuga heracleifolia)

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	New Cytotoxic Cycloartane Triterpenes from the Aerial Parts of Actaea heracleifolia (syn. Cimicifuga heracleifolia)
	Shi, Qiang-Qiang 1,2,3; Wang, Wei-Hua 1,2,3; Lu, Jing 1,2,3; Li, Da-Shan 1,3; Zhou, Lin 1,3; Qiu, Ming-Hua1,3
刊名	PLANTA MEDICA
	2019
卷号	85 期号:2 页码:154-159
关键词	Actaea heracleifolia Ranunculaceae 15 16-seco-cycloartane triterpene cycloartane triterpene glycosides cytotoxicity NMR
ISSN号	0032-0943
英文摘要	One new 15,16-seco-cycloartane triterpene (1), three new cycloartane triterpene glycosides (2-4), and five known compounds (5-9) were isolated from the aerial parts of Actaea heracleifolia. The chemical structures of these compounds were determined on the basis of NMR analysis, HRTOF-ESIMS data, and other spectroscopic methods. Selected compounds were evaluated for their cytotoxicity against human tumor cell lines (HL-60, SMMC-7721, A549, MCF-7, and SW480) in vitro. Compounds 3 and 4 showed weak activity against the HL-60, A-549, and MCF-7 cell lines with IC50 values ranging from 21.34 to 36.98 mu M.
资助项目	Autonomous Deployment Project of Kunming Institute of Botany, CAS[KIB2017010] ; Program for National Natural Science Foundation of China[U1132604] ; Program for National Natural Science Foundation of China[81302670] ; Major Program of CAS[KSZD-EW-Z-004-01]
语种	英语
资助机构	Autonomous Deployment Project of Kunming Institute of Botany, CAS ; Program for National Natural Science Foundation of China ; Major Program of CAS
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/64632]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Qiu, Ming-Hua
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 132 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Chinese Acad Sci, Yunnan Key Lab Nat Med Chem, Kunming, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Shi, Qiang-Qiang,Wang, Wei-Hua,Lu, Jing,et al. New Cytotoxic Cycloartane Triterpenes from the Aerial Parts of Actaea heracleifolia (syn. Cimicifuga heracleifolia)[J]. PLANTA MEDICA,2019,85(2):154-159.
APA	Shi, Qiang-Qiang,Wang, Wei-Hua,Lu, Jing,Li, Da-Shan,Zhou, Lin,&Qiu, Ming-Hua.(2019).New Cytotoxic Cycloartane Triterpenes from the Aerial Parts of Actaea heracleifolia (syn. Cimicifuga heracleifolia).PLANTA MEDICA,85(2),154-159.
MLA	Shi, Qiang-Qiang,et al."New Cytotoxic Cycloartane Triterpenes from the Aerial Parts of Actaea heracleifolia (syn. Cimicifuga heracleifolia)".PLANTA MEDICA 85.2(2019):154-159.