Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18
	Tang, Jian-Wei 1,2,3; Kong, Ling-Mei 1,2; Zu, Wen-Yu 4; Hu, Kun1,2 ; Li, Xiao-Nian 1,2; Yan, Bing-Chao 1,2; Wang, Wei-Guang 1,2; Sun, Han-Dong1,2 ; Li, Yan1,2 ; Puno, Pema-Tenzin1,2
刊名	ORGANIC LETTERS
	2019-02-01
卷号	21 期号:3 页码:771-775
ISSN号	1523-7060
英文摘要	Isopenicins A-C (1-3), three novel meroterpenoids possessing two types of unprecedented terpenoid-polyketide hybrid skeletons, were isolated from the cultures of Penicillium sp. sh18. Their structures were determined through synergetic use of extensive spectroscopic analysis, quantum-chemical calculation with ANN-PRA analysis, and X-ray crystallographic analysis. Additionally, the inhibitory activities of these compounds on the Wnt/beta-catenin signaling pathway were evaluated, and 1 was identified as a potent inhibitor of the Wnt signaling pathway.
资助项目	National Natural Science Foundation of China[81874298] ; National Natural Science Foundation of China[81673329] ; National Natural Science Foundation of China[81773783] ; National Natural Science Foundation of China[81603161]
语种	英语
资助机构	National Natural Science Foundation of China
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/64235]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Li, Yan; Puno, Pema-Tenzin
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Yunnan Univ Tradit Chinese Med, Kunming 650500, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Tang, Jian-Wei,Kong, Ling-Mei,Zu, Wen-Yu,et al. Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18[J]. ORGANIC LETTERS,2019,21(3):771-775.
APA	Tang, Jian-Wei.,Kong, Ling-Mei.,Zu, Wen-Yu.,Hu, Kun.,Li, Xiao-Nian.,...&Puno, Pema-Tenzin.(2019).Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18.ORGANIC LETTERS,21(3),771-775.
MLA	Tang, Jian-Wei,et al."Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18".ORGANIC LETTERS 21.3(2019):771-775.