Tricholopardins A and B, Anti-inflammatory Terpenoids from the Fruiting Bodies of Tricholoma pardinum
Feng, Tao1; Gan, Xiao-Qing1; Zhao, Yun-Li2; Zhang, Shuai-Bing1; Chen, He-Ping1; He, Juan1; Zheng, Yong-Sheng1; Sun, Huan1; Huang, Rong1; Li, Zheng-Hui1
刊名JOURNAL OF NATURAL PRODUCTS
2019
卷号82期号:1页码:45-50
ISSN号0163-3864
英文摘要Two new Tricholoma terpenoids, tricholopardins A and B, were isolated from the fruiting bodies of the basidiomycetes Tricholoma pardinum. Their structures were elucidated by spectroscopic methods, as well as electronic circular dichroism and optical rotatory dispersion calculations. Tricholopardin A potently inhibited nitric oxide production in lipopolysaccharide-induced RAW264.7 macrophages with an IC50 of 0.08 mu M. Its anti-inflammatory effects on three inflammatory mediators were also evaluated. A plausible biosynthetic pathway for these products is discussed.
资助项目National Natural Science Foundation of China[81872762] ; National Natural Science Foundation of China[31870513] ; National Natural Science Foundation of China[81561148013] ; National Natural Science Foundation of China[21502239] ; Key Projects of Technological Innovation of Hubei Province[2016ACA138] ; Fundamental Research Funds for the Central University, South-Central University for Nationalities[CZP18005] ; Fundamental Research Funds for the Central University, South-Central University for Nationalities[CZT18013] ; Fundamental Research Funds for the Central University, South-Central University for Nationalities[CZT18014] ; HPC of Kunming Institute of Botany ; Supercomputing Environment of Chinese Academy of Science (ScGrid)
语种英语
资助机构National Natural Science Foundation of China ; Key Projects of Technological Innovation of Hubei Province ; Fundamental Research Funds for the Central University, South-Central University for Nationalities ; HPC of Kunming Institute of Botany ; Supercomputing Environment of Chinese Academy of Science (ScGrid)
内容类型期刊论文
源URL[http://ir.kib.ac.cn/handle/151853/64189]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
通讯作者Li, Zheng-Hui; Liu, Ji-Kai
作者单位1.South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Hubei, Peoples R China
2.Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
推荐引用方式
GB/T 7714
Feng, Tao,Gan, Xiao-Qing,Zhao, Yun-Li,et al. Tricholopardins A and B, Anti-inflammatory Terpenoids from the Fruiting Bodies of Tricholoma pardinum[J]. JOURNAL OF NATURAL PRODUCTS,2019,82(1):45-50.
APA Feng, Tao.,Gan, Xiao-Qing.,Zhao, Yun-Li.,Zhang, Shuai-Bing.,Chen, He-Ping.,...&Liu, Ji-Kai.(2019).Tricholopardins A and B, Anti-inflammatory Terpenoids from the Fruiting Bodies of Tricholoma pardinum.JOURNAL OF NATURAL PRODUCTS,82(1),45-50.
MLA Feng, Tao,et al."Tricholopardins A and B, Anti-inflammatory Terpenoids from the Fruiting Bodies of Tricholoma pardinum".JOURNAL OF NATURAL PRODUCTS 82.1(2019):45-50.
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