Multidimensional liquid chromatography system with an innovative solvent evaporation interface

	Multidimensional liquid chromatography system with an innovative solvent evaporation interface
	Tian, Hongzhe; Xu, Jing; Xu, Yuan; Guan, Yafeng
刊名	journal of chromatography a
	2006-12-22
卷号	1137 期号:1 页码:42-48
关键词	two-dimensional liquid chromatography traditional Chinese medicines Angelica dahurica solvent exchange interface furancoumarin loop-valve interface band compression
通讯作者	关亚风
产权排序	1;1
英文摘要	an orthogonal two-dimensional liquid chromatographic (2d-lc) system was developed by using a vacuum-evaporation loop-type valve interface. normal-phase liquid chromatography (nplc) with a bonded cn phase column was used as the first dimension, and reversed-phase liquid chromatography (rplc) with a c-18 column was used as the second dimension. all the solvents in the loop of the interface were evaporated at 90 degrees c under vacuum conditions, leaving the analytes on the inner wall of the loop. the mobile phase of the second dimension dissolved the analytes in the loop and injected them onto the secondary column, allowing an on-line solvent exchange of a selected fraction from the first dimension to the second dimension. the chromatographic resolution of analytes on the two dimensions was maintained at their optimal condition. sample loss due to evaporation in the interface was observed that depended on the boiling point of the compound. separation of sixteen polycyclic aromatic hydrocarbon mixtures and a traditional chinese medicine angelica dahurica was demonstrated. (c) 2006 elsevier b.v. all rights reserved.
WOS标题词	science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]	biochemical research methods ; chemistry, analytical
研究领域[WOS]	biochemistry & molecular biology ; chemistry
关键词[WOS]	capillary columns ; separation ; hplc ; components ; mixtures
收录类别	SCI
原文出处	true
语种	英语
WOS记录号	WOS:000242872700007
公开日期	2010-11-30
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/98161]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	Chinese Acad Sci, Dalian Inst Chem Phys, Dept Instrumentat & Analyt Chem, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Tian, Hongzhe,Xu, Jing,Xu, Yuan,et al. Multidimensional liquid chromatography system with an innovative solvent evaporation interface[J]. journal of chromatography a,2006,1137(1):42-48.
APA	Tian, Hongzhe,Xu, Jing,Xu, Yuan,&Guan, Yafeng.(2006).Multidimensional liquid chromatography system with an innovative solvent evaporation interface.journal of chromatography a,1137(1),42-48.
MLA	Tian, Hongzhe,et al."Multidimensional liquid chromatography system with an innovative solvent evaporation interface".journal of chromatography a 1137.1(2006):42-48.