Deficiency of Gpr1 improves steroid hormone abnormality in hyperandrogenized mice

	Deficiency of Gpr1 improves steroid hormone abnormality in hyperandrogenized mice
	Yan Yu; Ya-Li Yang; Li-Feng Sun; Tian-Xia Xiao; Bao-Bei Wang; Pei-Gen Ren; Hui-Ru Tang; Jian V. Zhang
刊名	Reproductive Biology and Endocrinology
	2018
文献子类	期刊论文
英文摘要	DHEA treatment induced some aspects of PCOS in wild-type mice, such as increased body weight, elevated serum testosterone, increased number of small, cystic, atretic follicles, and absence of corpus luteum in ovaries. However, Gpr1 deficiency significantly attenuated the DHEA-induced weight gain and ovarian phenotype, improving steroidogenesis in ovaries and estradiol synthesis in cultured granulosa cells, partially through mTOR signaling. Conclusions
URL标识	查看原文
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/14693]
专题	深圳先进技术研究院_医药所
推荐引用方式 GB/T 7714	Yan Yu,Ya-Li Yang,Li-Feng Sun,et al. Deficiency of Gpr1 improves steroid hormone abnormality in hyperandrogenized mice[J]. Reproductive Biology and Endocrinology,2018.
APA	Yan Yu.,Ya-Li Yang.,Li-Feng Sun.,Tian-Xia Xiao.,Bao-Bei Wang.,...&Jian V. Zhang.(2018).Deficiency of Gpr1 improves steroid hormone abnormality in hyperandrogenized mice.Reproductive Biology and Endocrinology.
MLA	Yan Yu,et al."Deficiency of Gpr1 improves steroid hormone abnormality in hyperandrogenized mice".Reproductive Biology and Endocrinology (2018).