IR-780 dye loaded chemiluminescent organic nanoparticles with near-infrared emission for hydrogen peroxide detection and imaging

	IR-780 dye loaded chemiluminescent organic nanoparticles with near-infrared emission for hydrogen peroxide detection and imaging
	Tao Jiang; Yayun Wu; Hong Pan; Guanjun Deng; Pengfei Zhang; Ping Gong; Jianhai Chen; Lintao Cai
刊名	Nanomedicine: Nanotechnology, Biology and Medicine
	2018
文献子类	会议论文
英文摘要	Molecular imaging technology has been extensively applied in medical diagnosis, including MRI, CT, PET, ultrasonic imaging and near-infrared (NIR) optical imaging. Specially, NIR fluorescence imaging provides many advantages as a sensitive, economical, non-invasive, non-radiant technique for real-time in vivo monitoring of biological information. However, the utility of existing fluorescent probes for in vivo imaging is limited because they require excitation from external illumination sources to fluorescence, which results in a strong autofluorescence background and photobleaching. Chemiluminescence(CL) is the emission of luminescence as a result of chemical reaction without using an excitation light. Different from fluorescence, there is no background for chemiluminescence. In this work, we developed a new kind of chemiluminescence-generating near-infrared emissive organic nanoparticles by loading IR-780 and peroxyoxalate fuels together into lipid micelles, which showed great potential for in vivo H2O2detection and imaging.
URL标识	查看原文
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/14621]
专题	深圳先进技术研究院_医药所
推荐引用方式 GB/T 7714	Tao Jiang,Yayun Wu,Hong Pan,et al. IR-780 dye loaded chemiluminescent organic nanoparticles with near-infrared emission for hydrogen peroxide detection and imaging[J]. Nanomedicine: Nanotechnology, Biology and Medicine,2018.
APA	Tao Jiang.,Yayun Wu.,Hong Pan.,Guanjun Deng.,Pengfei Zhang.,...&Lintao Cai.(2018).IR-780 dye loaded chemiluminescent organic nanoparticles with near-infrared emission for hydrogen peroxide detection and imaging.Nanomedicine: Nanotechnology, Biology and Medicine.
MLA	Tao Jiang,et al."IR-780 dye loaded chemiluminescent organic nanoparticles with near-infrared emission for hydrogen peroxide detection and imaging".Nanomedicine: Nanotechnology, Biology and Medicine (2018).