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Analytical methods for nano-bio interface interactions
Wang, Jing; Quershi, Waseem Akthar; Li, Yiye; Xu, Jianxun; Nie, Guangjun
刊名Science china-chemistry
2016
卷号59期号:11页码:1467-1478
关键词Engineered nanomaterial Nano-bio interface Nano-bio interaction Analytical methods Protein corona Synchrotron radiation
ISSN号1674-7291
DOI10.1007/s11426-016-0340-1
通讯作者Nie, guangjun(niegj@nanoctr.cn)
英文摘要Knowledge on the interactions between engineered nanomaterials (enms) and biological systems is critical both for the assessment of biological effects of enms and for the rational design of enm-based products. however, probing the events that occur at the nano-bio interface remains extremely challenging due to their complex and dynamic nature. so far, the understanding of mechanisms underlying nano-bio interactions has been mainly limited by the lack of proper analytical techniques with sufficient sensitivity, selectivity and resolution for characterization of nano-bio interface events. moreover, many classic bioanalytical methods are not suitable for direct measurement of nano-bio interface interactions. these have made establishing analytical methodologies for systematic and comprehensive study of nano-bio interface one of the most focused areas in nanobiology. in this review we have discussed some representative developments regarding analytical techniques for nano-bio interface characterization, including the improvements of traditional methods and the emergence of powerful new technologies. these developments have allowed ultrasensitive, real-time analysis of interactions between enms and biomolecules, transformations of enms in biological environment, and impacts of enms on living systems on molecular or cellular level.
WOS关键词CT CONTRAST AGENTS ; SPIN-RESONANCE SPECTROSCOPY ; SILVER NANOPARTICLES ; PROTEIN CORONA ; GOLD NANOPARTICLES ; CARBON NANOTUBES ; PHYSICOCHEMICAL PROPERTIES ; HYDROGEN-PEROXIDE ; FLUORESCENT-PROBE ; OXIDATIVE STRESS
WOS研究方向Chemistry
WOS类目Chemistry, Multidisciplinary
语种英语
出版者SCIENCE PRESS
WOS记录号WOS:000387571100014
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/2176633
专题高能物理研究所
通讯作者Nie, Guangjun
作者单位Natl Ctr Nanosci & Technol, CAS Ctr Excellence Nanosci, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714
Wang, Jing,Quershi, Waseem Akthar,Li, Yiye,et al. Analytical methods for nano-bio interface interactions[J]. Science china-chemistry,2016,59(11):1467-1478.
APA Wang, Jing,Quershi, Waseem Akthar,Li, Yiye,Xu, Jianxun,&Nie, Guangjun.(2016).Analytical methods for nano-bio interface interactions.Science china-chemistry,59(11),1467-1478.
MLA Wang, Jing,et al."Analytical methods for nano-bio interface interactions".Science china-chemistry 59.11(2016):1467-1478.
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