Analytical methods for nano-bio interface interactions | |
Wang, Jing; Quershi, Waseem Akthar; Li, Yiye; Xu, Jianxun; Nie, Guangjun | |
刊名 | Science china-chemistry |
2016 | |
卷号 | 59期号:11页码:1467-1478 |
关键词 | Engineered nanomaterial Nano-bio interface Nano-bio interaction Analytical methods Protein corona Synchrotron radiation |
ISSN号 | 1674-7291 |
DOI | 10.1007/s11426-016-0340-1 |
通讯作者 | Nie, guangjun(niegj@nanoctr.cn) |
英文摘要 | Knowledge on the interactions between engineered nanomaterials (enms) and biological systems is critical both for the assessment of biological effects of enms and for the rational design of enm-based products. however, probing the events that occur at the nano-bio interface remains extremely challenging due to their complex and dynamic nature. so far, the understanding of mechanisms underlying nano-bio interactions has been mainly limited by the lack of proper analytical techniques with sufficient sensitivity, selectivity and resolution for characterization of nano-bio interface events. moreover, many classic bioanalytical methods are not suitable for direct measurement of nano-bio interface interactions. these have made establishing analytical methodologies for systematic and comprehensive study of nano-bio interface one of the most focused areas in nanobiology. in this review we have discussed some representative developments regarding analytical techniques for nano-bio interface characterization, including the improvements of traditional methods and the emergence of powerful new technologies. these developments have allowed ultrasensitive, real-time analysis of interactions between enms and biomolecules, transformations of enms in biological environment, and impacts of enms on living systems on molecular or cellular level. |
WOS关键词 | CT CONTRAST AGENTS ; SPIN-RESONANCE SPECTROSCOPY ; SILVER NANOPARTICLES ; PROTEIN CORONA ; GOLD NANOPARTICLES ; CARBON NANOTUBES ; PHYSICOCHEMICAL PROPERTIES ; HYDROGEN-PEROXIDE ; FLUORESCENT-PROBE ; OXIDATIVE STRESS |
WOS研究方向 | Chemistry |
WOS类目 | Chemistry, Multidisciplinary |
语种 | 英语 |
出版者 | SCIENCE PRESS |
WOS记录号 | WOS:000387571100014 |
内容类型 | 期刊论文 |
URI标识 | http://www.corc.org.cn/handle/1471x/2176633 |
专题 | 高能物理研究所 |
通讯作者 | Nie, Guangjun |
作者单位 | Natl Ctr Nanosci & Technol, CAS Ctr Excellence Nanosci, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Wang, Jing,Quershi, Waseem Akthar,Li, Yiye,et al. Analytical methods for nano-bio interface interactions[J]. Science china-chemistry,2016,59(11):1467-1478. |
APA | Wang, Jing,Quershi, Waseem Akthar,Li, Yiye,Xu, Jianxun,&Nie, Guangjun.(2016).Analytical methods for nano-bio interface interactions.Science china-chemistry,59(11),1467-1478. |
MLA | Wang, Jing,et al."Analytical methods for nano-bio interface interactions".Science china-chemistry 59.11(2016):1467-1478. |
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