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A strategy for rapid and facile fabrication of controlled, layered blood vessel-like structures
Wang, Nuoxin1,2,3; Tang, Lixue2,3; Zheng, Wenfu2,3; Peng, Yunhu2,3; Cheng, Shiyu2,3; Lei, Yifeng2,3; Zhang, Lingmin2,3; Hu, Bingfeng2,3; Liu, Shaoqin1; Zhang, Wei2,3
刊名Rsc advances
2016
卷号6期号:60页码:55054-55063
ISSN号2046-2069
DOI10.1039/c6ra12768a
通讯作者Liu, shaoqin(shaoqinliu@hit.edu.cn) ; Zhang, wei(zhangw@nanoctr.cn) ; Jiang, xingyu(xingyujiang@nanoctr.cn)
英文摘要We develop a rapid and facile method to fabricate tubular scaffolds by a single-step rolling operation. with the aid of fibrin medical glue and a smooth expanded polytetrafluoroethylene (eptfe) mandrel, we can wrap a piece of flat thin film into a three-dimensional (3d), multi-layered tubular structure with well-controlled diameter, wall thickness, and mechanical strength within 10 min. by patterning different cells in a pre-designed area on the film, after rolling, we can obtain blood vessel-mimicking tissues with well-arranged, multilayered 3d architectures within 70 min. our strategy provides an excellent platform to rapidly fabricate tubular scaffolds essentially with no equipment and straightforward manipulations.
WOS关键词ADULT ARTERIAL REVASCULARIZATION ; ENGINEERED VASCULAR GRAFTS ; 3-DIMENSIONAL TISSUES ; SOFT LITHOGRAPHY ; FIBRIN GEL ; IN-VITRO ; SCAFFOLD ; TECHNOLOGY ; BIOLOGY ; CELLS
WOS研究方向Chemistry
WOS类目Chemistry, Multidisciplinary
语种英语
出版者ROYAL SOC CHEMISTRY
WOS记录号WOS:000378274800052
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/2176500
专题高能物理研究所
通讯作者Liu, Shaoqin; Zhang, Wei; Jiang, Xingyu
作者单位1.Harbin Inst Technol, Sch Life Sci & Technol, 2 Yikuang Rd, Harbin 150001, Peoples R China
2.Beijing Engn Res Ctr BioNanotechnol, 11 Beiyitiao, Beijing 100190, Peoples R China
3.Natl Ctr NanoSci & Technol, CAS Key Lab Biol Effects Nanomat & Nanosafety, CAS Ctr Excellence Nanosci, 11 Beiyitiao, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714
Wang, Nuoxin,Tang, Lixue,Zheng, Wenfu,et al. A strategy for rapid and facile fabrication of controlled, layered blood vessel-like structures[J]. Rsc advances,2016,6(60):55054-55063.
APA Wang, Nuoxin.,Tang, Lixue.,Zheng, Wenfu.,Peng, Yunhu.,Cheng, Shiyu.,...&Jiang, Xingyu.(2016).A strategy for rapid and facile fabrication of controlled, layered blood vessel-like structures.Rsc advances,6(60),55054-55063.
MLA Wang, Nuoxin,et al."A strategy for rapid and facile fabrication of controlled, layered blood vessel-like structures".Rsc advances 6.60(2016):55054-55063.
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