A strategy for rapid and facile fabrication of controlled, layered blood vessel-like structures | |
Wang, Nuoxin1,2,3; Tang, Lixue2,3; Zheng, Wenfu2,3; Peng, Yunhu2,3; Cheng, Shiyu2,3; Lei, Yifeng2,3; Zhang, Lingmin2,3; Hu, Bingfeng2,3; Liu, Shaoqin1; Zhang, Wei2,3 | |
刊名 | Rsc advances
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2016 | |
卷号 | 6期号:60页码:55054-55063 |
ISSN号 | 2046-2069 |
DOI | 10.1039/c6ra12768a |
通讯作者 | Liu, shaoqin(shaoqinliu@hit.edu.cn) ; Zhang, wei(zhangw@nanoctr.cn) ; Jiang, xingyu(xingyujiang@nanoctr.cn) |
英文摘要 | We develop a rapid and facile method to fabricate tubular scaffolds by a single-step rolling operation. with the aid of fibrin medical glue and a smooth expanded polytetrafluoroethylene (eptfe) mandrel, we can wrap a piece of flat thin film into a three-dimensional (3d), multi-layered tubular structure with well-controlled diameter, wall thickness, and mechanical strength within 10 min. by patterning different cells in a pre-designed area on the film, after rolling, we can obtain blood vessel-mimicking tissues with well-arranged, multilayered 3d architectures within 70 min. our strategy provides an excellent platform to rapidly fabricate tubular scaffolds essentially with no equipment and straightforward manipulations. |
WOS关键词 | ADULT ARTERIAL REVASCULARIZATION ; ENGINEERED VASCULAR GRAFTS ; 3-DIMENSIONAL TISSUES ; SOFT LITHOGRAPHY ; FIBRIN GEL ; IN-VITRO ; SCAFFOLD ; TECHNOLOGY ; BIOLOGY ; CELLS |
WOS研究方向 | Chemistry |
WOS类目 | Chemistry, Multidisciplinary |
语种 | 英语 |
出版者 | ROYAL SOC CHEMISTRY |
WOS记录号 | WOS:000378274800052 |
内容类型 | 期刊论文 |
URI标识 | http://www.corc.org.cn/handle/1471x/2176500 |
专题 | 高能物理研究所 |
通讯作者 | Liu, Shaoqin; Zhang, Wei; Jiang, Xingyu |
作者单位 | 1.Harbin Inst Technol, Sch Life Sci & Technol, 2 Yikuang Rd, Harbin 150001, Peoples R China 2.Beijing Engn Res Ctr BioNanotechnol, 11 Beiyitiao, Beijing 100190, Peoples R China 3.Natl Ctr NanoSci & Technol, CAS Key Lab Biol Effects Nanomat & Nanosafety, CAS Ctr Excellence Nanosci, 11 Beiyitiao, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Wang, Nuoxin,Tang, Lixue,Zheng, Wenfu,et al. A strategy for rapid and facile fabrication of controlled, layered blood vessel-like structures[J]. Rsc advances,2016,6(60):55054-55063. |
APA | Wang, Nuoxin.,Tang, Lixue.,Zheng, Wenfu.,Peng, Yunhu.,Cheng, Shiyu.,...&Jiang, Xingyu.(2016).A strategy for rapid and facile fabrication of controlled, layered blood vessel-like structures.Rsc advances,6(60),55054-55063. |
MLA | Wang, Nuoxin,et al."A strategy for rapid and facile fabrication of controlled, layered blood vessel-like structures".Rsc advances 6.60(2016):55054-55063. |
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