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	Full assessment of fate and physiological behavior of quantum dots utilizing caenorhabditis elegans as a model organism
	Qu, Ying2; Li, Wei3; Zhou, Yunlong1; Liu, Xuefeng1; Zhang, Lili2; Wang, Liming2; Li, Yu-feng3; Iida, Atsuo4; Tang, Zhiyong1; Zhao, Yuliang2,3
刊名	Nano letters
	2011-08-01
卷号	11期号:8页码:3174-3183
关键词	C. elegans Quantum dots Biodistribution Chemical speciation In vivo imaging Reproductive toxicity
ISSN号	1530-6984
DOI	10.1021/nl201391e
通讯作者	Tang, zhiyong(zytang@nanoctr.cn)
英文摘要	We evaluated the in vivo fate and physiological behavior of quantum dots (qds) in caenorhabditis elegans by gfp transfection, fluorescent imaging, synchrotron radiation based elemental imaging, and speciation techniques. the in situ metabolism and degradation of qds in the alimentary system and long-term toxicity on reproduction are fully assessed. this work highlights the utility of the c. elegans model as a multi-flexible platform to allow noninvasively imaging and monitoring in vivo consequences of engineered nanomaterials.
WOS关键词	X-RAY-FLUORESCENCE ; IN-VIVO ; C-ELEGANS ; CARBON NANOTUBES ; LIFE-SPAN ; NANOPARTICLES ; NANOCRYSTALS ; TOXICITY ; SPECTROSCOPY ; NANOSTRUCTURES
WOS研究方向	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS类目	Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000293665600021
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2176084
专题	高能物理研究所
通讯作者	Tang, Zhiyong
作者单位	1.Natl Ctr Nanosci & Technol, Lab Nanomat, Beijing 100190, Peoples R China 2.Natl Ctr Nanosci & Technol, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China 3.Chinese Acad Sci, CAS Key Lab Nucl Analyt Tech, Inst High Energy Phys, Beijing 100049, Peoples R China 4.High Energy Accelerator Org, Photon Factory, Tsukuba, Ibaraki 3050801, Japan
推荐引用方式 GB/T 7714	Qu, Ying,Li, Wei,Zhou, Yunlong,et al. Full assessment of fate and physiological behavior of quantum dots utilizing caenorhabditis elegans as a model organism[J]. Nano letters,2011,11(8):3174-3183.
APA	Qu, Ying.,Li, Wei.,Zhou, Yunlong.,Liu, Xuefeng.,Zhang, Lili.,...&Chen, Chunying.(2011).Full assessment of fate and physiological behavior of quantum dots utilizing caenorhabditis elegans as a model organism.Nano letters,11(8),3174-3183.
MLA	Qu, Ying,et al."Full assessment of fate and physiological behavior of quantum dots utilizing caenorhabditis elegans as a model organism".Nano letters 11.8(2011):3174-3183.

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