Antibiotics and Antibiotic Resistance Genes in Sediment of Honghu Lake and East Dongting Lake, China

doi:10.1007/s00248-016-0814-9

CORC > 武汉植物园 > 中国科学院武汉植物园

	Antibiotics and Antibiotic Resistance Genes in Sediment of Honghu Lake and East Dongting Lake, China
	Yang, Yuyi 1; Cao, Xinhua 1,2; Lin, Hui 3; Wang, Jun 1,4
刊名	MICROBIAL ECOLOGY
	2016-11-01
卷号	72 期号:4 页码:791-801
关键词	Sulfonamides Tetracyclines Antibiotic resistance gene Honghu lake East dongting lake
ISSN号	0095-3628
DOI	10.1007/s00248-016-0814-9
英文摘要	Sediment is an ideal medium for the aggregation and dissemination of antibiotics and antibiotic resistance genes (ARGs). The levels of antibiotics and ARGs in Honghu Lake and East Dongting Lake of central China were investigated in this study. The concentrations of eight antibiotics (four sulfonamides and four tetracyclines) in Honghu Lake were in the range 90.00-437.43 mu g kg(-1) (dry weight (dw)) with mean value of 278.21 mu g kg(-1) dw, which was significantly higher than those in East Dongting Lake (60.02-321.04 mu g kg(-1) dw, mean value of 195.70 mu g kg(-1) dw). Among the tested three sulfonamide resistance genes (sul) and eight tetracycline resistance genes (tet), sul1, sul2, tetA, tetC, and tetM had 100 % detection frequency in sediment samples of East Dongting Lake, while only sul1, sul2, and tetC were observed in all samples of Honghu Lake. The relative abundance of sul2 was higher than that of sul1 at p < 0.05 level in both lakes. The relative abundance of tet genes in East Dongting Lake was in the following order: tetM > tetB > tetC > tetA. The relative abundance of sul1, sul2, and tetC in East Dongting Lake was significantly higher than those in Honghu Lake. The abundance of background bacteria may play an important role in the horizontal spread of sul2 and tetC genes in Honghu Lake and sul1 in East Dongting Lake, respectively. Redundancy analysis indicated that tetracyclines may play a more important role than sulfonamides in the abundance of sul1, sul2, and tetC gens in Honghu Lake and East Dongting Lake.
资助项目	National Natural Science Foundation of China[31400113] ; National Natural Science Foundation of China[41401542] ; Sino-Africa Joint Research Center, Chinese Academy of Sciences[Y623321K01] ; Knowledge Innovation Program of the Chinese Academy of Sciences[Y455436K02] ; Youth Innovation Promotion Association of Chinese Academy of Sciences[2015282] ; Hundred Talents Program of the Chinese Academy of Sciences[Y329671K01]
WOS研究方向	Environmental Sciences & Ecology ; Marine & Freshwater Biology ; Microbiology
语种	英语
出版者	SPRINGER
WOS记录号	WOS:000386775700006
内容类型	期刊论文
源URL	[http://202.127.146.157/handle/2RYDP1HH/14]
专题	中国科学院武汉植物园
通讯作者	Wang, Jun
作者单位	1.Chinese Acad Sci, Wuhan Bot Garden, Key Lab Aquat Bot & Watershed Ecol, Wuhan 430074, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Zhejiang Acad Agr Sci, Inst Environm Resources & Soil Fertilizers, Hangzhou 310021, Zhejiang, Peoples R China 4.Chinese Acad Sci, Sino Africa Joint Res Ctr, Wuhan 430074, Peoples R China
推荐引用方式 GB/T 7714	Yang, Yuyi,Cao, Xinhua,Lin, Hui,et al. Antibiotics and Antibiotic Resistance Genes in Sediment of Honghu Lake and East Dongting Lake, China[J]. MICROBIAL ECOLOGY,2016,72(4):791-801.
APA	Yang, Yuyi,Cao, Xinhua,Lin, Hui,&Wang, Jun.(2016).Antibiotics and Antibiotic Resistance Genes in Sediment of Honghu Lake and East Dongting Lake, China.MICROBIAL ECOLOGY,72(4),791-801.
MLA	Yang, Yuyi,et al."Antibiotics and Antibiotic Resistance Genes in Sediment of Honghu Lake and East Dongting Lake, China".MICROBIAL ECOLOGY 72.4(2016):791-801.