Pyroelectric nanoplatform for NIR-II-triggered photothermal therapy with simultaneous pyroelectric dynamic therapy | |
Tang, Zhongmin1; Zhao, Peiran2; Ni, Dalong1; Liu, Yanyan2; Zhang, Meng1; Wang, Han1; Zhang, Hua3; Gao, Hongbo4; Yao, Zhenwei; Bu, Wenbo2 | |
刊名 | MATERIALS HORIZONS |
2018 | |
卷号 | 5期号:5页码:946 |
ISSN号 | 2051-6347 |
DOI | 10.1039/c8mh00627j |
英文摘要 | Photothermal therapy (PTT) has been attracting much attention because of its high efficiency and ease of use. Currently deployed PTT, however, shows two main deficiencies: limited penetration depth and interference from heat shock proteins (HSPs). Here we describe a specific application of a pyroelectric material, specifically SnSe-polyvinylpyrrolidone (SnSe-PVP) nanorods, for tumor photoacoustic imaging and PTT, accompanied by pyroelectric dynamic therapy (PEDT), utilizing near-infrared-II (NIR-II) light as the excitation trigger. Moreover, we used PEDT to generate reactive oxygen species (ROS) from SnSe-PVP nanorods and to have the ROS attack HSPs and cancer cells during heating and cooling. This work revealed a high potential for the application of pyroelectric materials in biomedicine, especially for PTT with PEDT via NIR-II light stimulation. |
学科主题 | Chemistry, Multidisciplinary ; Materials Science, Multidisciplinary |
出版者 | ROYAL SOC CHEMISTRY |
WOS记录号 | WOS:000444245600018 |
资助机构 | This work was financially supported by the National Funds for Distinguished Young Scientists (Grant No. 51725202) and National Science Foundation for the Young Scientists of China (Grant No. 51702211), the Shanghai Excellent Academic Leaders Program (Grant No. 16XD1404000). ; This work was financially supported by the National Funds for Distinguished Young Scientists (Grant No. 51725202) and National Science Foundation for the Young Scientists of China (Grant No. 51702211), the Shanghai Excellent Academic Leaders Program (Grant No. 16XD1404000). |
内容类型 | 期刊论文 |
源URL | [http://ir.sic.ac.cn/handle/331005/24688] |
专题 | 中国科学院上海硅酸盐研究所 |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.East China Normal Univ, Sch Chem & Mol Engn, Shanghai Key Lab Green Chem & Chem Proc, Shanghai 200062, Peoples R China 4.Fudan Univ, Huashan Hosp, Dept Radiol, Shanghai 200040, Peoples R China 5.Fudan Univ, Shanghai Canc Ctr, Dept Radiol, Shanghai 200032, Peoples R China |
推荐引用方式 GB/T 7714 | Tang, Zhongmin,Zhao, Peiran,Ni, Dalong,et al. Pyroelectric nanoplatform for NIR-II-triggered photothermal therapy with simultaneous pyroelectric dynamic therapy[J]. MATERIALS HORIZONS,2018,5(5):946, 952. |
APA | Tang, Zhongmin.,Zhao, Peiran.,Ni, Dalong.,Liu, Yanyan.,Zhang, Meng.,...&Bu, Wenbo.(2018).Pyroelectric nanoplatform for NIR-II-triggered photothermal therapy with simultaneous pyroelectric dynamic therapy.MATERIALS HORIZONS,5(5),946. |
MLA | Tang, Zhongmin,et al."Pyroelectric nanoplatform for NIR-II-triggered photothermal therapy with simultaneous pyroelectric dynamic therapy".MATERIALS HORIZONS 5.5(2018):946. |
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