A reversible light-responsive assembly system based on host-guest interaction for controlled release

doi:10.1039/c8nj00014j

	A reversible light-responsive assembly system based on host-guest interaction for controlled release
	Yu, Jiemiao 1; Qu, Hongnan 1,2,3; Dong, Tingting 1,3; Rong, Meng 1,3; Yang, Liangrong 1; Liu, Huizhou 1,2
刊名	NEW JOURNAL OF CHEMISTRY
	2018-04-21
卷号	42 期号:8 页码:6532-6537
ISSN号	1144-0546
DOI	10.1039/c8nj00014j
文献子类	Article
英文摘要	Here, we established a reversible light-responsive assembly system, which consisted of azobenzene grafted mesoporous silica nanoparticles (MSN-AZO) and cyclodextrin-functionalized Au nanoparticles (AuNP@CD). The assembly system was constructed by the host-guest interaction between azobenzene and beta-cyclodextrin. For controlled release, the cargo molecule fluorescein isothiocyanate (FITC) in the pores of the MSNs can be regulated or triggered by different wavelengths. Under visible light irradiation, the azobenzene on the MSN surface exhibits a trans-configuration, and can bind with b-cyclodextrin on the AuNPs by host-guest interaction. Thus the mesopores were closed by the AuNP@CD caps and cargo molecules were locked in the pores. While under UV irradiation, the azobenzene changed to cis-configuration, which cannot bind with b-cyclodextrin, leading to the disaggregation of the caps from the outer surface of the MSNs. Thus the cargo molecules were released from the pores. This light-responsive triggered system may have potential applications in drug-controlled release, light-responsive devices and novel catalytic processes.
WOS关键词	MESOPOROUS SILICA NANOPARTICLES ; INTRACELLULAR CONTROLLED-RELEASE ; DRUG-RELEASE ; GOLD NANOPARTICLES ; CANCER-CELLS ; DELIVERY ; NANOCONTAINERS ; RECOGNITION ; OXIDE ; WATER
WOS研究方向	Chemistry
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000430996700098
资助机构	National Natural Science Foundation of China(21676273) ; National Key Natural Science Foundation of China(U1507203) ; National Technology Research and Development Program of China(2015CB251402) ; Youth Innovation Promotion Association, CAS(2016043)
内容类型	期刊论文
源URL	[http://ir.qibebt.ac.cn/handle/337004/11465]
专题	中国科学院青岛生物能源与过程研究所
通讯作者	Yang, Liangrong
作者单位	1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, CAS Key Lab Green Proc & Engn, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao 266101, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Yu, Jiemiao,Qu, Hongnan,Dong, Tingting,et al. A reversible light-responsive assembly system based on host-guest interaction for controlled release[J]. NEW JOURNAL OF CHEMISTRY,2018,42(8):6532-6537.
APA	Yu, Jiemiao,Qu, Hongnan,Dong, Tingting,Rong, Meng,Yang, Liangrong,&Liu, Huizhou.(2018).A reversible light-responsive assembly system based on host-guest interaction for controlled release.NEW JOURNAL OF CHEMISTRY,42(8),6532-6537.
MLA	Yu, Jiemiao,et al."A reversible light-responsive assembly system based on host-guest interaction for controlled release".NEW JOURNAL OF CHEMISTRY 42.8(2018):6532-6537.