2,3-Dialdehyde nanofibrillated cellulose as a potential material for the treatment of MRSA infection
Mou, Kaiwen1,2,3; Li, Juanjuan1,2,4; Wang, Yunyun1,2; Cha, Ruitao1,2; Jiang, Xingyu1,2,5
刊名JOURNAL OF MATERIALS CHEMISTRY B
2017-10-14
卷号5期号:38页码:7876-7884
DOI10.1039/c7tb01857f
文献子类Article
英文摘要Nanocellulose materials have undergone rapid development in recent years as promising biomedical materials due to their excellent physical and biological properties, in particular their biocompatibility, biodegradability, and low cytotoxicity. In this study, we prepared 2,3-dialdehyde nanofibrillated cellulose (DANFC) by sodium periodate oxidation, which is a mild oxidation process. With increasing oxidation time, the antimicrobial activity of DANFC against both Staphylococcus aureus (S. aureus) and methicillin-resistant Staphylococcus aureus (MRSA) improved. DANFC also displays good biocompatibility with mammalian cells, and shows good blood compatibility. In addition, animal studies and histology results reveal that DANFC can accelerate wound healing and enhance the formation of blood vessels and epithelium.
WOS关键词STAPHYLOCOCCUS-AUREUS ; GOLD NANOPARTICLES ; SILVER NANOPARTICLES ; BACTERIAL CELLULOSE ; GROWTH BOUNDARIES ; NANOCELLULOSE ; PH ; ANTIBIOTICS ; RESISTANCE ; COMPOSITE
WOS研究方向Materials Science
语种英语
WOS记录号WOS:000412233000011
资助机构Independent Innovation and Achievement Transformation Project in Shandong Province(2014CGZH0303) ; National Science Foundation of China(81361140345 ; CAS(XDA09030305) ; 21535001)
内容类型期刊论文
源URL[http://ir.qibebt.ac.cn/handle/337004/9745]  
专题青岛生物能源与过程研究所_其他文献
作者单位1.Natl Ctr Nanosci & Technol, Beijing Engn Res Ctr BioNanotechnol, Beijing 100190, Peoples R China
2.Natl Ctr Nanosci & Technol, CAS Ctr Excellence Nanosci, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China
3.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao 266101, Peoples R China
4.China Univ Geosci, Sch Mat Sci & Technol, Beijing 100083, Peoples R China
5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Mou, Kaiwen,Li, Juanjuan,Wang, Yunyun,et al. 2,3-Dialdehyde nanofibrillated cellulose as a potential material for the treatment of MRSA infection[J]. JOURNAL OF MATERIALS CHEMISTRY B,2017,5(38):7876-7884.
APA Mou, Kaiwen,Li, Juanjuan,Wang, Yunyun,Cha, Ruitao,&Jiang, Xingyu.(2017).2,3-Dialdehyde nanofibrillated cellulose as a potential material for the treatment of MRSA infection.JOURNAL OF MATERIALS CHEMISTRY B,5(38),7876-7884.
MLA Mou, Kaiwen,et al."2,3-Dialdehyde nanofibrillated cellulose as a potential material for the treatment of MRSA infection".JOURNAL OF MATERIALS CHEMISTRY B 5.38(2017):7876-7884.
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