An in vitro synthetic biosystem based on acetate for production of phloroglucinol

doi:10.1186/s12896-017-0376-z

CORC > 青岛生物能源与过程研究所 > 中国科学院青岛生物能源与过程研究所 > 材料生物技术研究中心

	An in vitro synthetic biosystem based on acetate for production of phloroglucinol
	Zhang, Rubing 1,2; Liu, Wei 1; Cao, Yujin 1; Xu, Xin 1,2; Xian, Mo 1; Liu, Huizhou 1
刊名	BMC BIOTECHNOLOGY
	2017-08-08
卷号	17
关键词	In Vitro Acetate Acetyl-coa Synthetase Phloroglucinol High Yield
DOI	10.1186/s12896-017-0376-z
文献子类	Article
英文摘要	Background: Phloroglucinol is an important chemical, and the biosynthesis processes which can convert glucose to phloroglucinol have been established. However, due to approximate 80% of the glucose being transformed into undesirable by-products and biomass, this biosynthesis process only shows a low yield with the highest value of about 0.20 g/g. The industrial applications are usually hindered by the low current productivity and yield and also by the high costs. Generally, several different aspects limit the development of phloroglucinol biosynthesis. The yield of phloroglucinol is one of the most important parameters for its bioconversion especially from economic and ecological points of view. The in vitro biosynthesis of bio-based chemicals, is a flexible alternative with potentially high-yield to in vivo biosynthetic technology.
WOS关键词	ENGINEERING ESCHERICHIA-COLI ; ACETYL-COA CARBOXYLASE ; ACID ; BIOSYNTHESIS ; COENZYME ; GLYCEROL ; FERMENTATION ; ACCUMULATION ; EXPRESSION ; CHEMICALS
WOS研究方向	Biotechnology & Applied Microbiology
语种	英语
WOS记录号	WOS:000408016900001
资助机构	National Natural Science Foundation of China(21376255 ; Taishan Scholars Climbing Program of Shandong(tspd20150210) ; 21572242)
内容类型	期刊论文
源URL	[http://ir.qibebt.ac.cn/handle/337004/9553]
专题	青岛生物能源与过程研究所_材料生物技术研究中心
作者单位	1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biobased Mat, Qingdao 266101, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Rubing,Liu, Wei,Cao, Yujin,et al. An in vitro synthetic biosystem based on acetate for production of phloroglucinol[J]. BMC BIOTECHNOLOGY,2017,17.
APA	Zhang, Rubing,Liu, Wei,Cao, Yujin,Xu, Xin,Xian, Mo,&Liu, Huizhou.(2017).An in vitro synthetic biosystem based on acetate for production of phloroglucinol.BMC BIOTECHNOLOGY,17.
MLA	Zhang, Rubing,et al."An in vitro synthetic biosystem based on acetate for production of phloroglucinol".BMC BIOTECHNOLOGY 17(2017).