Ultrathin Cell-Membrane-Mimic Phosphorylcholine Polymer Film Coating Enables Large Improvements for InVivo Electrochemical Detection

	Ultrathin Cell-Membrane-Mimic Phosphorylcholine Polymer Film Coating Enables Large Improvements for InVivo Electrochemical Detection
	Liu, Xiaomeng 2; Xiao, Tongfang 1; Wu, Fei 1; Shen, Mo-Yuan 3; Zhang, Meining 2; Yu, Hsiao-hua 3; Mao, Lanqun 1
刊名	ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
	2017-09-18
卷号	56 期号:39 页码:11802-11806
关键词	Antifouling Dopamine Electropolymerization Invivo Studies Phosphocholine
英文摘要	Resisting biomolecule adsorption onto the surface of brain-implanted microelectrodes is a key issue for invivo monitoring of neurochemicals. Herein, we demonstrate that an ultrathin cell-membrane-mimic film of ethylenedioxythiophene tailored with zwitterionic phosphorylcholine (EDOT-PC) electropolymerized onto the surface of a carbon fiber microelectrode (CFE) not only resists protein adsorption but also maintains the sensitivity and time response for invivo monitoring of dopamine (DA). As a consequence, the as-prepared PEDOT-PC/CFEs could be used as a new reliable platform for tracking DA invivo and would help understand the physiological and pathological functions of DA.
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/41063]
专题	化学研究所_活体分析化学实验室
作者单位	1.Chinese Acad Sci, Beijing Natl Lab Mol Sci, Key Lab Analyt Chem Living Biosyst, Inst Chem, Beijing 100190, Peoples R China 2.Renmin Univ China, Dept Chem, Beijing 100872, Peoples R China 3.Acad Sinica, Inst Chem, 128 Acad Rd,Sec 2, Taipei 11529, Taiwan
推荐引用方式 GB/T 7714	Liu, Xiaomeng,Xiao, Tongfang,Wu, Fei,et al. Ultrathin Cell-Membrane-Mimic Phosphorylcholine Polymer Film Coating Enables Large Improvements for InVivo Electrochemical Detection[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2017,56(39):11802-11806.
APA	Liu, Xiaomeng.,Xiao, Tongfang.,Wu, Fei.,Shen, Mo-Yuan.,Zhang, Meining.,...&Mao, Lanqun.(2017).Ultrathin Cell-Membrane-Mimic Phosphorylcholine Polymer Film Coating Enables Large Improvements for InVivo Electrochemical Detection.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,56(39),11802-11806.
MLA	Liu, Xiaomeng,et al."Ultrathin Cell-Membrane-Mimic Phosphorylcholine Polymer Film Coating Enables Large Improvements for InVivo Electrochemical Detection".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 56.39(2017):11802-11806.