POSS-modified PEG adhesives for wound closure

	POSS-modified PEG adhesives for wound closure
	Bu, Ya-zhong 1,2; Sun, Guo-fei 3; Zhang, Li-cheng 3; Liu, Jian-heng 3; Yang, Fei 1,2; Tang, Pei-fu 3; Wu, De-cheng 1,2
刊名	CHINESE JOURNAL OF POLYMER SCIENCE
	2017-10-01
卷号	35 期号:10 页码:1231-1242
关键词	Adhesives Peg Poss Hydrogel Wound Closure
英文摘要	PEG-related adhesives are limited in clinical use because they are easy to swell and cannot support the cell growth. In this study, we produced a series of POSS-modified PEG adhesives with high adhesive strength. Introduction of inorganic hydrophobic POSS units decreased the swelling of the adhesives and enhanced cell adhesion and growth. The in vitro cytotoxicity and in vivo inflammatory response experiments clearly demonstrated that the adhesives were nontoxic and possessed excellent biocompatibility. Compared with the sutured wounds, the adhesive-treated wounds showed an accelerated healing process in wounded skin model of the Bama miniature pig, demonstrating that the POSS-modified PEG adhesive is a promising candidate for wound closure.
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/39320]
专题	化学研究所_高分子物理与化学实验室
作者单位	1.Chinese Acad Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Peoples Liberat Army Gen Hosp, Dept Orthopaed, Beijing 100853, Peoples R China
推荐引用方式 GB/T 7714	Bu, Ya-zhong,Sun, Guo-fei,Zhang, Li-cheng,et al. POSS-modified PEG adhesives for wound closure[J]. CHINESE JOURNAL OF POLYMER SCIENCE,2017,35(10):1231-1242.
APA	Bu, Ya-zhong.,Sun, Guo-fei.,Zhang, Li-cheng.,Liu, Jian-heng.,Yang, Fei.,...&Wu, De-cheng.(2017).POSS-modified PEG adhesives for wound closure.CHINESE JOURNAL OF POLYMER SCIENCE,35(10),1231-1242.
MLA	Bu, Ya-zhong,et al."POSS-modified PEG adhesives for wound closure".CHINESE JOURNAL OF POLYMER SCIENCE 35.10(2017):1231-1242.