Fluorescence chemosensing of water-soluble Ag-14 nanoclusters for lysozyme and Hg2+ ions

CORC > 化学研究所 > 中国科学院化学研究所 > 分子动态与稳态结构实验室

	Fluorescence chemosensing of water-soluble Ag-14 nanoclusters for lysozyme and Hg2+ ions
	Ding, Weihua 1,2; Guan, Lingmei 1; Han, Juanjuan 1; Mangala, Rajini 1; Luo, Zhixun 1,2
刊名	SENSORS AND ACTUATORS B-CHEMICAL
	2017-10-01
卷号	250 页码:364-371
关键词	Ag-14 Ncs Nbo Analysis Fluorescence Chemosensing Lysozyme Hg2++++ Detection Bioimaging
英文摘要	Employing glutathione (HSG) as a protecting ligand, we have synthesized water-soluble and biocompatible Ag-14(SG)(12) nanoclusters (Ag-14 NCs) of which the composition and structure are determined via high-resolution mass spectrometry, fingerprint spectroscopy and DFT calculations. Natural bond orbital (NBO) analysis on a basis of first-principles theoretical calculations demonstrates the donor-acceptor orbital overlaps and charge-transfer interactions between silver and the ligand HSG. Further, it is interestingly found that the fluorescence of Ag-14 NCs can be largely enhanced at the presence of lysozyme distinguishing from other proteases which we have tested, revealing the feasibility of Ag-14 NCs as chemosensing to identify lysozyme. Also found is that, the fluorescence on-state of the obtained Ag14NCs-Lys can be exclusively switched off at the addition of Hg2+ ions with an ultralow detection limit of similar to 16.2 nM. This interesting finding reveals Ag-14 NCs a versatile chemosensor to identify lysozyme from proteases and to detect mercury ions from various cations. (C) 2017 Elsevier B.V. All rights reserved.
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/38934]
专题	化学研究所_分子动态与稳态结构实验室
作者单位	1.Chinese Acad Sci, Inst Chem, State Key Lab Struct Chem Unstable & Stable Speci, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Ding, Weihua,Guan, Lingmei,Han, Juanjuan,et al. Fluorescence chemosensing of water-soluble Ag-14 nanoclusters for lysozyme and Hg2+ ions[J]. SENSORS AND ACTUATORS B-CHEMICAL,2017,250:364-371.
APA	Ding, Weihua,Guan, Lingmei,Han, Juanjuan,Mangala, Rajini,&Luo, Zhixun.(2017).Fluorescence chemosensing of water-soluble Ag-14 nanoclusters for lysozyme and Hg2+ ions.SENSORS AND ACTUATORS B-CHEMICAL,250,364-371.
MLA	Ding, Weihua,et al."Fluorescence chemosensing of water-soluble Ag-14 nanoclusters for lysozyme and Hg2+ ions".SENSORS AND ACTUATORS B-CHEMICAL 250(2017):364-371.