Photoswitchable and Water-Soluble Fluorescent Nano-Aggregates Based on a Diarylethene-Dansyl Dyad and Liposome

CORC > 化学研究所 > 中国科学院化学研究所 > 分子纳米结构与纳米技术实验室

	Photoswitchable and Water-Soluble Fluorescent Nano-Aggregates Based on a Diarylethene-Dansyl Dyad and Liposome
	Cheng, Hongbo 1; Ma, Pin 2; Wang, Yanan 2; Hu, Guofei 1; Fang, Shibi 2; Fang, Yanyan 2; Lin, Yuan 2
刊名	CHEMISTRY-AN ASIAN JOURNAL
	2017
卷号	12 期号:2 页码:248-253
关键词	Liposomes Molecular Switch Nano-aggregates Optical Stimuli Photochromism
英文摘要	In this work, a unique approach is developed to generate photoswitchable and water-soluble fluorescent nano-aggregates. Initially, a new light-controlled diarylethene-dansyl dyad DAE 1 is formed by linking two dansyl fluorophores covalently to a symmetrical dithienylethene backbone, whose photophysical properties can be reversibly switched by optical stimuli. Subsequently, the water insolubility of the molecular switch 1 is overcome by incorporating it into the bilayer of liposome DPPC (1,2-dihexadecanoyl-sn-glycero-3-phosphocholine) in water. This strategy creates stable fluorescent nano-aggregates OF-1@DPPC (approximate to 25nm diameter) that are soluble in an aqueous medium. The nano-aggregates OF-1@DPPC retain and even improve the photoswitchable fluorescence properties of DAE 1. More importantly, OF-1@DPPC exhibits a remarkable photostability and fatigue resistance after 5 cycles of irradiation with UV and visible light, which is crucial for its practical application.
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/38054]
专题	化学研究所_分子纳米结构与纳米技术实验室
作者单位	1.Chinese Acad Sci, Inst High Energy Phys, Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Beijing Natl Lab Mol Sci, Key Lab Photochem, Inst Chem, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Cheng, Hongbo,Ma, Pin,Wang, Yanan,et al. Photoswitchable and Water-Soluble Fluorescent Nano-Aggregates Based on a Diarylethene-Dansyl Dyad and Liposome[J]. CHEMISTRY-AN ASIAN JOURNAL,2017,12(2):248-253.
APA	Cheng, Hongbo.,Ma, Pin.,Wang, Yanan.,Hu, Guofei.,Fang, Shibi.,...&Lin, Yuan.(2017).Photoswitchable and Water-Soluble Fluorescent Nano-Aggregates Based on a Diarylethene-Dansyl Dyad and Liposome.CHEMISTRY-AN ASIAN JOURNAL,12(2),248-253.
MLA	Cheng, Hongbo,et al."Photoswitchable and Water-Soluble Fluorescent Nano-Aggregates Based on a Diarylethene-Dansyl Dyad and Liposome".CHEMISTRY-AN ASIAN JOURNAL 12.2(2017):248-253.