Novel Reaction-Based Fluorescence Probes for the Detection of Hydrogen Sulfide in Living Cells

	Novel Reaction-Based Fluorescence Probes for the Detection of Hydrogen Sulfide in Living Cells
	Zhao, Zhensheng 1; Cao, Lixia 1; Zhang, Tao 1; Hu, Rui 1; Wang, Shuangqing 1; Li, Shayu 1; Li, Yi 2; Yang, Guoqiang 1
刊名	CHEMISTRYSELECT
	2016-07-16
卷号	1 期号:11 页码:2581-2585
关键词	Fluorescence Probes Hydrogen Sulfide Tetrazine Group Bodipy 3t3 Fibroblast Cells
英文摘要	Hydrogen Sulfide (H2S), a kind of important gas signal molecules, serves as an important medium in physiological and pathological studies. It is also a hot spot in the research of chemistry and biology. We now report a new type of reactionbased fluorescent probe for selective detecting H2S in living cells that adopts H2S reaction with tetrazine group (Tz) to dihydio-tetrazine. The fluorescence probes, BODIPY-Tz-I and BODIPY-Tz-II (BODIPY: abbreviation for boron-dipyrromethene), respond to H2S by a turn-on fluorescence signal enhancement and show high selectivity of H2S over other biologically species. BODIPY-Tz-I and BODIPY-Tz-II can be used to detect H2S in both buffer solution and cells in vivo, which provide a novel and effective approach for H2S detection in biological systems.
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/37930]
专题	化学研究所_高分子物理与化学实验室
作者单位	1.Univ Chinese Acad Sci, Chinese Acad Sci, Inst Chem,Beijing Natl Lab Mol Sci, Key Lab Photochem, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Tech Inst Phys & Chem, Key Lab Photochem Convers & Optoelect Mat, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Zhensheng,Cao, Lixia,Zhang, Tao,et al. Novel Reaction-Based Fluorescence Probes for the Detection of Hydrogen Sulfide in Living Cells[J]. CHEMISTRYSELECT,2016,1(11):2581-2585.
APA	Zhao, Zhensheng.,Cao, Lixia.,Zhang, Tao.,Hu, Rui.,Wang, Shuangqing.,...&Yang, Guoqiang.(2016).Novel Reaction-Based Fluorescence Probes for the Detection of Hydrogen Sulfide in Living Cells.CHEMISTRYSELECT,1(11),2581-2585.
MLA	Zhao, Zhensheng,et al."Novel Reaction-Based Fluorescence Probes for the Detection of Hydrogen Sulfide in Living Cells".CHEMISTRYSELECT 1.11(2016):2581-2585.