Upregulation of Melanogenesis and Tyrosinase Activity: Potential Agents for Vitiligo | |
Niu, C (Niu, Chao); Aisa, HA (Aisa, Haji A.) | |
刊名 | MOLECULES |
2017 | |
卷号 | 22期号:8页码:1-28 |
关键词 | Melanogenesis Tyrosinase Activity Vitiligo Plant Extracts Natural Products Synthesized Derivatives Analogues |
ISSN号 | 1420-3049 |
DOI | 10.3390/molecules22081303 |
英文摘要 | Melanin, the compound primarily responsible in humans for hair, eye and skin pigmentation, is produced by melanocytes through a complicated process called melanogenesis that is catalyzed by tyrosinase and other tyrosinase-related proteins. The abnormal loss of melanin causes dermatological problems such as vitiligo. Hence the regulation of melanogenesis and tyrosinase activity is very important for treating hypopigmentary disorders. Many melanogenesis stimulators have been discovered during the past decade. This article reviews recent advances in research on extracts and active ingredients of plants, synthesized compounds with stimulating effect on melanin synthesis and tyrosinase activity, as well as their influence on the expression of related proteins and possible signaling pathways for the design and development of novel anti-vitiligo agents. |
内容类型 | 期刊论文 |
源URL | [http://ir.xjipc.cas.cn/handle/365002/5047] |
专题 | 新疆理化技术研究所_省部共建新疆特有药用资源利用重点实验室 新疆理化技术研究所_资源化学研究室 |
通讯作者 | Aisa, HA (Aisa, Haji A.) |
作者单位 | 1.Chinese Acad Sci, Key Lab Plant Resources & Chem Arid Zone, Urumqi 830011, Peoples R China 2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plant, Urumqi 830011, Peoples R China |
推荐引用方式 GB/T 7714 | Niu, C ,Aisa, HA . Upregulation of Melanogenesis and Tyrosinase Activity: Potential Agents for Vitiligo[J]. MOLECULES,2017,22(8):1-28. |
APA | Niu, C ,&Aisa, HA .(2017).Upregulation of Melanogenesis and Tyrosinase Activity: Potential Agents for Vitiligo.MOLECULES,22(8),1-28. |
MLA | Niu, C ,et al."Upregulation of Melanogenesis and Tyrosinase Activity: Potential Agents for Vitiligo".MOLECULES 22.8(2017):1-28. |
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