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	Three New Polyynes from Codonopsis pilosula and Their Activities on Lipid Metabolism
	Hu, Xiao-Yu1,2; Qin, Fu-Ying2,3; Lu, Xi-Feng2; Zhang, Lan-Sheng1; Cheng, Yong-Xian2,4,5
刊名	MOLECULES
	2018-04-01
卷号	23期号:4页码:887
关键词	Codonopsis Pilosula Choushenpilosulynes A-c Lipid Metabolism
ISSN号	1420-3049
DOI	10.3390/molecules23040887
英文摘要	Three new polyynes, named choushenpilosulynes A-C (1-3), were isolated from an 85% aqueous EtOH extract of the roots of Codonopsis pilosula cultivated in Xundian County of Yunnan province, China. Their structures, including the absolute configuration of the glucose residue in 1 and 2, were determined by spectroscopic analysis and gas chromatography (GC). In addition, biological evaluation shows that all the compounds can inhibit the expression of the squalene monooxygenase (SQLE) gene in HepG2 cells, suggesting that these compounds may be involved in lipid metabolism.
语种	英语
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/61372]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Dali Univ, Sch Pharm & Chem, Dali 671000, Peoples R China 2.Shenzhen Univ, Sch Pharmaceut Sci, Guangdong Key Lab Genome Stabil & Dis Prevent, Hlth Sci Ctr,Sch Med, Shenzhen 518060, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 4.Henan Univ Chinese Med, Sch Pharm, Zhengzhou 450008, Henan, Peoples R China 5.Chengdu Univ Tradit Chinese Med, Coll Pharm, Chengdu 610075, Sichuan, Peoples R China
推荐引用方式 GB/T 7714	Hu, Xiao-Yu,Qin, Fu-Ying,Lu, Xi-Feng,et al. Three New Polyynes from Codonopsis pilosula and Their Activities on Lipid Metabolism[J]. MOLECULES,2018,23(4):887.
APA	Hu, Xiao-Yu,Qin, Fu-Ying,Lu, Xi-Feng,Zhang, Lan-Sheng,&Cheng, Yong-Xian.(2018).Three New Polyynes from Codonopsis pilosula and Their Activities on Lipid Metabolism.MOLECULES,23(4),887.
MLA	Hu, Xiao-Yu,et al."Three New Polyynes from Codonopsis pilosula and Their Activities on Lipid Metabolism".MOLECULES 23.4(2018):887.

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