Design, synthesis and cytotoxicity of nitrogen-containing tanshinone derivatives

doi:10.1016/j.tetlet.2017.11.046

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Design, synthesis and cytotoxicity of nitrogen-containing tanshinone derivatives
	Li, Ming-Ming 1,2,4; Xia, Fan 1,2,3,4; Li, Cheng-Ji 1,2,3; Xu, Gang1,2 ; Qin, Hong-Bo1,2
刊名	TETRAHEDRON LETTERS
	2018-01-03
卷号	59 期号:1 页码:46-48
关键词	Tanshinones Heterocyclic Compounds Cytotoxicity
ISSN号	0040-4039
DOI	10.1016/j.tetlet.2017.11.046
英文摘要	Tanshinones were used as starting material to synthesize a small library of nitrogen heterocyclic derivatives featured with oxazole, imidazole, and pyrazine ring between C-11/C-12 by simple methods. Except for salviamine A and isosalviamine A, 22 new derivatives were synthesized. Their structures were confirmed by spectroscopic analysis. Moreover, 11 derivatives exhibited moderate cytotoxic activities against five human cancer lines in vitro. (C) 2017 Elsevier Ltd. All rights reserved.
语种	英语
WOS记录号	WOS:000423006200010
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/60591]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Yunnan Baiyao Grp Corp Ltd, Kunming 650032, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Li, Ming-Ming,Xia, Fan,Li, Cheng-Ji,et al. Design, synthesis and cytotoxicity of nitrogen-containing tanshinone derivatives[J]. TETRAHEDRON LETTERS,2018,59(1):46-48.
APA	Li, Ming-Ming,Xia, Fan,Li, Cheng-Ji,Xu, Gang,&Qin, Hong-Bo.(2018).Design, synthesis and cytotoxicity of nitrogen-containing tanshinone derivatives.TETRAHEDRON LETTERS,59(1),46-48.
MLA	Li, Ming-Ming,et al."Design, synthesis and cytotoxicity of nitrogen-containing tanshinone derivatives".TETRAHEDRON LETTERS 59.1(2018):46-48.