Melodinines A-G, Monoterpenoid Indole Alkaloids from Melodinus henryi

doi:10.1021/np900595v

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Melodinines A-G, Monoterpenoid Indole Alkaloids from Melodinus henryi
	Feng, Tao 1,2; Cai, Xiang-Hai1 ; Liu, Ya-Ping 1,2; Li, Yan1 ; Wang, Yuan-Yuan 1; Luo, Xiao-Dong1
刊名	JOURNAL OF NATURAL PRODUCTS
	2010
卷号	73 期号:1 页码:22-26
关键词	Anti-hiv Activity Var. Propinqua Unique Skeleton Lancifolia Micrantha Schiartane Chinensis
ISSN号	0163-3864
DOI	10.1021/np900595v
文献子类	Article
英文摘要	Nineteen monoterpenoid indole alkaloids including seven new ones, melodinines A-G (1-7), were isolated from Melodinus henryi. The structures of the new compounds were elucidated using spectroscopic methods, and the Structure of compound 4 was confirmed by single-crystal X-ray diffraction analysis. The known compounds were identified by comparing their spectroscopic data with those reported in the literature. All of the compounds were evaluated for cytotoxic activity against live human cancer cell lines, and compound 11 exhibited cytotoxicity against HL-60, SMMC-7721, A-549, and SK-BR-3 cells with IC(50) values of 2.0, 16.8, 25.9. and 24.7 mu M, respectively.
学科主题	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS关键词	ALSTONIA-SCHOLARIS ; LEAVES ; CULTURE ; PICHON
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy
语种	英语
WOS记录号	WOS:000273654000006
资助机构	National Basic Research Program of China [2009CB522300]; Chinese Academy of Science
公开日期	2012-03-21
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/4888]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Feng, Tao,Cai, Xiang-Hai,Liu, Ya-Ping,et al. Melodinines A-G, Monoterpenoid Indole Alkaloids from Melodinus henryi[J]. JOURNAL OF NATURAL PRODUCTS,2010,73(1):22-26.
APA	Feng, Tao,Cai, Xiang-Hai,Liu, Ya-Ping,Li, Yan,Wang, Yuan-Yuan,&Luo, Xiao-Dong.(2010).Melodinines A-G, Monoterpenoid Indole Alkaloids from Melodinus henryi.JOURNAL OF NATURAL PRODUCTS,73(1),22-26.
MLA	Feng, Tao,et al."Melodinines A-G, Monoterpenoid Indole Alkaloids from Melodinus henryi".JOURNAL OF NATURAL PRODUCTS 73.1(2010):22-26.