Dibenzocyclooctadiene Lignans from Schisandra wilsoniana and Their Anti-HIV-1 Activities

doi:10.1021/np100067w

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Dibenzocyclooctadiene Lignans from Schisandra wilsoniana and Their Anti-HIV-1 Activities
	Guang-Yu Yang; Yin-Ke Li; Rui-Rui Wang; Xiao-Nian Li; Wei-Lie Xiao; Liu-Meng Yang; Jian-Xin Pu; Yong-Tang Zheng; Han-Dong Sun
刊名	JOURNAL OF NATURAL PRODUCTS
	2010-05-01
卷号	73 期号:5 页码:915-919
关键词	Schizandra-chinensis Baill Anti-hiv Activity Kadsura-longipedunculata Absolute Structure Gomisin-g Constituents Interior Fruits
ISSN号	0163-3864
DOI	10.1021/np100067w
文献子类	Article
英文摘要	Twelve new dibenzocyclooctadiene lignans, marlignans A-L (1-12), together with 16 known compounds, were isolated from the leaves and stems of Schisandra wilsoniana. The structures of 1-12 were elucidated by spectroscopic methods including 1D- and 2D-NMR techniques. Compounds 1-12 were evaluated for their anti-HIV activities, of which compounds 3, 6, 8, and 12 showed modest activities with therapeutic index values of 13.2, 15.6, 17.6, and 16.4, respectively.
学科主题	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS关键词	SCHIZANDRA-CHINENSIS BAILL ; ANTI-HIV ACTIVITY ; KADSURA-LONGIPEDUNCULATA ; ABSOLUTE STRUCTURE ; GOMISIN-G ; CONSTITUENTS ; INTERIOR ; FRUITS
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy
语种	英语
WOS记录号	WOS:000278080900023
资助机构	NSFC [30830115, 20802082]; Chinese Academy of Sciences [KSCX1-YW-R-24]; 973 Program [2009CB522303, 2009CB522306, 2009CB940900]; Scientific and Technological Projects of China [2009ZX09501-029]; Young Academic and Technical Leader Rising Foundation of Yunnan Province [2006PY01-47]; Natural Science Foundation of Yunnan Province [2005XY04, 2006B0042Q]
公开日期	2012-03-21
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/4230]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Guang-Yu Yang,Yin-Ke Li,Rui-Rui Wang,et al. Dibenzocyclooctadiene Lignans from Schisandra wilsoniana and Their Anti-HIV-1 Activities[J]. JOURNAL OF NATURAL PRODUCTS,2010,73(5):915-919.
APA	Guang-Yu Yang.,Yin-Ke Li.,Rui-Rui Wang.,Xiao-Nian Li.,Wei-Lie Xiao.,...&Han-Dong Sun.(2010).Dibenzocyclooctadiene Lignans from Schisandra wilsoniana and Their Anti-HIV-1 Activities.JOURNAL OF NATURAL PRODUCTS,73(5),915-919.
MLA	Guang-Yu Yang,et al."Dibenzocyclooctadiene Lignans from Schisandra wilsoniana and Their Anti-HIV-1 Activities".JOURNAL OF NATURAL PRODUCTS 73.5(2010):915-919.