Chemical Constituents from the Leaves and Stems of Schisandra rubriflora

doi:10.1021/np900849y

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Chemical Constituents from the Leaves and Stems of Schisandra rubriflora
	Wei-Lie Xiao; Shi-Ying Yang; Liu-Meng Yang; Guang-Yu Yang; Rui-Rui Wang; Hai-Bo Zhang; Wei Zhao; Jian-Xin Pu; Yang Lu; Yong-Tang Zheng
刊名	JOURNAL OF NATURAL PRODUCTS
	2010-02-01
卷号	73 期号:2 页码:221-225
关键词	Highly Oxygenated Nortriterpenoids Anti-hiv Activity Dibenzocyclooctadiene Lignans Structure Elucidation Chinensis Schisanartane Triterpenoids Lancifolia Micrantha Acid
ISSN号	0163-3864
DOI	10.1021/np900849y
文献子类	Article
英文摘要	Six new nortriterpenoids, schirubridilactones A-F (1-6). as well as 14 known compounds, were isolated from the leaves and stems of Schisandra rubriflora. The Structures of 1-6 were elucidated oil the basis of spectroscopic methods including HSQC, HMBC, (1)H-(1)H COSY, and ROESY NMR experiments. The relative stereochemistry of I was confirmed through single-crystal X-ray analysis. In addition, compounds 1-6 showed anti-HIV-1 activity with EC(50) values in the range 14.3-80.8 mu g/mL and Selectivity indices in the range 2.2-9.0.
学科主题	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS关键词	HIGHLY OXYGENATED NORTRITERPENOIDS ; ANTI-HIV ACTIVITY ; DIBENZOCYCLOOCTADIENE LIGNANS ; STRUCTURE ELUCIDATION ; CHINENSIS ; SCHISANARTANE ; TRITERPENOIDS ; LANCIFOLIA ; MICRANTHA ; ACID
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy
语种	英语
WOS记录号	WOS:000274803600025
资助机构	NSFC [20802082, 30830115]; Chinese Academy of Sciences [KSCX1-YW-R-24]; Major State Basic Research Development program of China [2009CB522303, 2009CB940900]; Young Academic and Technical Leader Rising Foundation of Yunnan province [2006PY0147]; Natural Science Foundation of Yunnan Province [2005XY04, 2006B0042Q]
公开日期	2012-03-21
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/4226]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Wei-Lie Xiao,Shi-Ying Yang,Liu-Meng Yang,et al. Chemical Constituents from the Leaves and Stems of Schisandra rubriflora[J]. JOURNAL OF NATURAL PRODUCTS,2010,73(2):221-225.
APA	Wei-Lie Xiao.,Shi-Ying Yang.,Liu-Meng Yang.,Guang-Yu Yang.,Rui-Rui Wang.,...&Han-Dong Sun.(2010).Chemical Constituents from the Leaves and Stems of Schisandra rubriflora.JOURNAL OF NATURAL PRODUCTS,73(2),221-225.
MLA	Wei-Lie Xiao,et al."Chemical Constituents from the Leaves and Stems of Schisandra rubriflora".JOURNAL OF NATURAL PRODUCTS 73.2(2010):221-225.