Antibacterial activities of neolignans isolated from the seed endotheliums of Trewia nudiflora
Li, GH; Zhao, PJ; Shen, YM; Zhang, KQ
刊名ACTA BOTANICA SINICA
2004-09-01
卷号46期号:9页码:1122-1127
关键词Trewia Nudiflora Seed Endothelium Neolignan Antibacterial Activity
ISSN号1672-6650
文献子类Article
英文摘要Five neolignans including four new ones were obtained from the seed endotheliums of Trewia nudiflora L. Their structures were determined to be 9'-methyl americanol A (1), 9'-methyl isoamericanol A (2), 9'-ethyl americanol A (3), 9'-butyl americanol A (4), and americanin (5). Two acetylated products 3,4diacetyl americanin (5a) and 3,4,9-triacetyl americanin (5b) had been prepared from compound 5. All of these compounds were investigated on antibacterial assays when carbenicillin sodium, streptomycin sulfate and rifampicin were used as positive controls. Compounds 4 and 5 exhibited antibacterial activities against gram-positive bacterium Staphylococcus aureus and gram-negative bacterium Mycobacteriurn tuberculosis at the minimum inhibitory concentrations (MIC) of 50 mug/mL and 100 mug/mL, respectively, but 5a and 5b did not exhibit antibacterial activity at 200 mug/disk.
学科主题Biochemistry & Molecular Biology ; Plant Sciences
WOS关键词MAYTANSINOID TUMOR INHIBITORS
WOS研究方向Biochemistry & Molecular Biology ; Plant Sciences
语种英语
WOS记录号WOS:000224034800016
公开日期2012-03-21
内容类型期刊论文
源URL[http://ir.kib.ac.cn:8080/handle/151853/4220]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
2.Yunnan Univ, Lab Conservat & Utilizat Bio Resource, Kunming 650091, Peoples R China
推荐引用方式
GB/T 7714
Li, GH,Zhao, PJ,Shen, YM,et al. Antibacterial activities of neolignans isolated from the seed endotheliums of Trewia nudiflora[J]. ACTA BOTANICA SINICA,2004,46(9):1122-1127.
APA Li, GH,Zhao, PJ,Shen, YM,&Zhang, KQ.(2004).Antibacterial activities of neolignans isolated from the seed endotheliums of Trewia nudiflora.ACTA BOTANICA SINICA,46(9),1122-1127.
MLA Li, GH,et al."Antibacterial activities of neolignans isolated from the seed endotheliums of Trewia nudiflora".ACTA BOTANICA SINICA 46.9(2004):1122-1127.
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