Four new podocarpane-type trinorditerpenes from Aleurites moluccana

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Four new podocarpane-type trinorditerpenes from Aleurites moluccana
	Liu, Hai-Yang; Li, Shi-Jin ; Zhao, Yi ; Ni, Wei ; Hao, Xiao-Jiang; Li, Jun-Zhu ; Hua, Yan ; Xie, Bai-Bo ; Qing, Chen ; Chen, Chang-Xiang
刊名	HELVETICA CHIMICA ACTA
	2007
卷号	90 期号:10 页码:2017-2023
关键词	Azadirachta-indica Taiwania-cryptomerioides Stem Bark Tricyclic Diterpenoids Constituents Assay
ISSN号	0018-019X
文献子类	Article
英文摘要	Four new podocarpane-type trinorditerpenenes, (5 beta,10 alpha)-12,13-dihydroxypodocarpa-8,11,13-trien-3-one (1), (5 beta,10 alpha)-12-hydroxy-13-methoxypodocarpa-8,11,13-trien-3-one (2), (5 beta,10 alpha)-13-hydroxy-12-methoxypodocarpa-8,11,13-trien-3-one (3), and (3 alpha,5 beta,10 alpha)-13-methoxypodocarpa-8,11,13-triene-3,12-diol (4), together with four known diterpenes, 12-hydroxy-13-methylpodocarpa-8,11,13-trien-3-one (5), spruceanol (6), ent-3 alpha-hydroxypimara-8(14),15-dien-12-one (7), and ent-3 beta,14 alpha-hydroxypimara-7,9(11),15-triene-12-one (8), were isolated from the twigs and leaves of Aleurites moluccana. Their structures were elucidated by means of comprehensive spectroscopic analyses, including NMR and MS. Except 8, all compounds were evaluated for their cytotoxicity; compound 4 exhibited moderate inhibitory activity against Raji cells with an IC50 value of 4.24 mu g/ml.
学科主题	Chemistry ; Multidisciplinary
WOS关键词	AZADIRACHTA-INDICA ; TAIWANIA-CRYPTOMERIOIDES ; STEM BARK ; TRICYCLIC DITERPENOIDS ; CONSTITUENTS ; ASSAY
WOS研究方向	Chemistry
语种	英语
WOS记录号	WOS:000250496100016
公开日期	2011-11-24
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn:8080/handle/151853/1971]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Kunming Med Coll, Yunnan Key Lab Pharmacol Nat Prod Res, Kunming 650031, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 3.SW Forest Coll, Kunming 650224, Peoples R China
推荐引用方式 GB/T 7714	Liu, Hai-Yang,Li, Shi-Jin,Zhao, Yi,et al. Four new podocarpane-type trinorditerpenes from Aleurites moluccana[J]. HELVETICA CHIMICA ACTA,2007,90(10):2017-2023.
APA	Liu, Hai-Yang.,Li, Shi-Jin.,Zhao, Yi.,Ni, Wei.,Hao, Xiao-Jiang.,...&Chen, Chang-Xiang.(2007).Four new podocarpane-type trinorditerpenes from Aleurites moluccana.HELVETICA CHIMICA ACTA,90(10),2017-2023.
MLA	Liu, Hai-Yang,et al."Four new podocarpane-type trinorditerpenes from Aleurites moluccana".HELVETICA CHIMICA ACTA 90.10(2007):2017-2023.