Xanthoquinodins from the Endolichenic Fungal Strain Chaetomium elatum
Chen, Guo-Dong1,4; Chen, Ying1; Gao, Hao1; Shen, Li-Qing1; Wu, Yang1; Li, Xiao-Xia1; Li, Yan2; Guo, Liang-Dong3; Cen, Ying-Zhou4; Yao, Xin-Sheng1
刊名JOURNAL OF NATURAL PRODUCTS
2013-04-01
卷号76期号:4页码:702-709
关键词Cercospora-beticola Toxins Humicola Sp Proliferation Assay
ISSN号0163-3864
DOI10.1021/np400041y
通讯作者Gao, H (reprint author), Jinan Univ, Coll Pharm, Inst Tradit Chinese Med & Nat Prod, Guangzhou 510632, Guangdong, Peoples R China. ; tghao@jnu.edu.cn ; tyaoxs@jnu.edu.cn
文献子类Article
英文摘要Five new xanthoquinodins, A4-A6 (1-3), B4 (4), and B5 (5), were isolated from the crude extract of the endolichenic fungal strain Chaetomium elatum (No. 63-10-3-1), along with three known xanthoquinodins, A1-A3 (6-8). Their structures were determined by detailed spectroscopic analysis and comparison of the NMR data with those of the closely related compounds previously reported. The absolute configuration of 1 was established by X-ray crystallographic analysis and ECD calculation. The cytotoxic activity of all compounds was tested against HL-60, SMMC-7721, A-549, MCF-7, and SW480 human cancer cell lines.
学科主题Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS关键词CERCOSPORA-BETICOLA TOXINS ; HUMICOLA SP ; PROLIFERATION ; ASSAY
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000318264700030
资助机构Ministry of Science and Technology of China [2009CB522300, 2012ZX09301002-003]; Natural Science Foundation of China [81202441]; program for New Century Excellent Talents in University from the Ministry of Education of China [NCET-10-0120]; high-performance computing platform of Jinan University ; Ministry of Science and Technology of China(2009CB522300 ; Natural Science Foundation of China(81202441) ; program for New Century Excellent Talents in University from the Ministry of Education of China(NCET-10-0120) ; high-performance computing platform of Jinan University ; 2012ZX09301002-003)
公开日期2013-07-24
内容类型期刊论文
源URL[http://ir.kib.ac.cn:8080/handle/151853/16551]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Jinan Univ, Coll Pharm, Inst Tradit Chinese Med & Nat Prod, Guangzhou 510632, Guangdong, Peoples R China
2.Chinese Acad Sci, State Key Lab Photochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650204, Peoples R China
3.Chinese Acad Sci, Inst Microbiol, State Key Lab Mycol, Beijing 100190, Peoples R China
4.Jinan Univ, Dept Chem, Guangzhou 510632, Guangdong, Peoples R China
推荐引用方式
GB/T 7714
Chen, Guo-Dong,Chen, Ying,Gao, Hao,et al. Xanthoquinodins from the Endolichenic Fungal Strain Chaetomium elatum[J]. JOURNAL OF NATURAL PRODUCTS,2013,76(4):702-709.
APA Chen, Guo-Dong.,Chen, Ying.,Gao, Hao.,Shen, Li-Qing.,Wu, Yang.,...&Yao, Xin-Sheng.(2013).Xanthoquinodins from the Endolichenic Fungal Strain Chaetomium elatum.JOURNAL OF NATURAL PRODUCTS,76(4),702-709.
MLA Chen, Guo-Dong,et al."Xanthoquinodins from the Endolichenic Fungal Strain Chaetomium elatum".JOURNAL OF NATURAL PRODUCTS 76.4(2013):702-709.
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