An additive-multiplicative mean residual life model for right-censored data
Cai, Jingheng1; He, Haijin2; Song, Xinyuan3,4; Sun, Liuquan5
刊名BIOMETRICAL JOURNAL
2017-05-01
卷号59期号:3页码:579-592
关键词Additive-multiplicative model Estimating equations Mean residual life function Survival data
ISSN号0323-3847
DOI10.1002/bimj.201600068
英文摘要Many studies have focused on determining the effect of the body mass index (BMI) on the mortality in different cohorts. In this article, we propose an additive-multiplicative mean residual life (MRL) model to assess the effects of BMI and other risk factors on the MRL function of survival time in a cohort of Chinese type 2 diabetic patients. The proposed model can simultaneously manage additive and multiplicative risk factors and provide a comprehensible interpretation of their effects on the MRL function of interest. We develop an estimation procedure through pseudo partial score equations to obtain parameter estimates. We establish the asymptotic properties of the proposed estimators and conduct simulations to demonstrate the performance of the proposed method. The application of the procedure to a study on the life expectancy of type 2 diabetic patients reveals new insights into the extension of the life expectancy of such patients.
资助项目National Natural Science Foundation of China[11471277] ; National Natural Science Foundation of China[11690015] ; National Natural Science Foundation of China[11101443] ; National Natural Science Foundation of China[11231010] ; Research Grant Council of the Hong Kong Special Administration Region[14601115] ; Chinese University of Hong Kong, Key Laboratory of RCSDS, CAS[2008DP173182] ; BCMIIS ; high-performance grid computing platform of Sun Yat-sen University
WOS研究方向Mathematical & Computational Biology ; Mathematics
语种英语
出版者WILEY
WOS记录号WOS:000400569800013
内容类型期刊论文
源URL[http://ir.amss.ac.cn/handle/2S8OKBNM/26074]  
专题中国科学院数学与系统科学研究院
通讯作者Song, Xinyuan
作者单位1.Sun Yat Sen Univ, Dept Stat, Guangzhou, Guangdong, Peoples R China
2.Shenzhen Univ, Coll Math & Stat, Shenzhen, Peoples R China
3.Chinese Univ Hong Kong, Shenzhen Res Inst, Hong Kong, Hong Kong, Peoples R China
4.Chinese Univ Hong Kong, Dept Stat, Hong Kong, Hong Kong, Peoples R China
5.Chinese Acad Sci, Inst Appl Math, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Cai, Jingheng,He, Haijin,Song, Xinyuan,et al. An additive-multiplicative mean residual life model for right-censored data[J]. BIOMETRICAL JOURNAL,2017,59(3):579-592.
APA Cai, Jingheng,He, Haijin,Song, Xinyuan,&Sun, Liuquan.(2017).An additive-multiplicative mean residual life model for right-censored data.BIOMETRICAL JOURNAL,59(3),579-592.
MLA Cai, Jingheng,et al."An additive-multiplicative mean residual life model for right-censored data".BIOMETRICAL JOURNAL 59.3(2017):579-592.
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