Doxorubicin accelerates and enhances AAV-based transgene expression in the cat and rat brain | |
Gong Hongliang1,2; Lu Yiliang1; Qian Liling1; I.Andolina1; Liu Rui3; Zhang Shenghai3; Zilong Qiu1; Wu Jihong3; Wang Wei1 | |
2017-07 | |
会议日期 | 2017.7.2 |
会议地点 | 曲阜 |
关键词 | AAV doxorubicin gene transfer cat visual cortex |
英文摘要 |
PURPOSE: Recombinant adeno-associated viruses (AAV) are widely used vectors for gene transfer into the central nervous system (CNS).However, Low transduction efficiency andthe delay in transgene expression have hampered it from wide application in such as early embryonic development and the brain of higher mammals for both basic and clinic researches. This study is designed to establish a new means to improve both the efficiency and timing of AAV transduction in transgene expression. |
语种 | 英语 |
内容类型 | 会议论文 |
源URL | [http://ir.psych.ac.cn/handle/311026/22106] |
专题 | 心理所主办学术会议_2017年第二届曲阜视觉科学会议_会议摘要 |
通讯作者 | Wu Jihong; Wang Wei |
作者单位 | 1.Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, Chinese Academy of Sciences 2.University of Chinese Academy of Sciences 3.Department of Ophthalmology, EYE and ENT Hospital of Fudan University, Key Laboratory of Myopia of State Health Ministry and Key Laboratory of Visual Impairment and Restoration of Shanghai |
推荐引用方式 GB/T 7714 | Gong Hongliang,Lu Yiliang,Qian Liling,et al. Doxorubicin accelerates and enhances AAV-based transgene expression in the cat and rat brain[C]. 见:. 曲阜. 2017.7.2. |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论