Graphene oxide-based fluorescent "turn-on" strategy for Hg2+ detection by using catalytic hairpin assembly for amplification

doi:10.1016/j.snb.2017.04.134

CORC > 重庆绿色智能技术研究院 > 中国科学院重庆绿色智能技术研究院 > 太赫兹技术研究中心

	Graphene oxide-based fluorescent "turn-on" strategy for Hg2+ detection by using catalytic hairpin assembly for amplification
	Yun, Wen 1; Xiong, Wei 3; Wu, Hong 1; Fu, Min 1; Huang, Yu4 ; Liu, Xingyan 1; Yang, Lizhu 2
刊名	SENSORS AND ACTUATORS B-CHEMICAL
	2017-10-01
卷号	249 页码:493-498
关键词	Hairpins Graphene oxide Catalytic hairpin assembly Hg2+ detection
ISSN号	0925-4005
DOI	10.1016/j.snb.2017.04.134
通讯作者	Yun, W (reprint author), Chongqing Technol & Business Univ, Coll Environm & Resources, Chongqing Key Lab Catalysis & Funct Organ Mol, Chongqing 400067, Peoples R China. ; Yang, LZ (reprint author), Wenzhou Med Univ, Sch Pharmaceut Sci, Wenzhou 325035, Zhejiang, Peoples R China.
英文摘要	We have reported an enzyme-free amplification fluorescent strategy for ultra-sensitive detection of Hg2+ based on graphene oxide (GO) and catalytic hairpins self-assembly. Three fluorophore labled metastable hairpin DNA probes can be closely adsorbed onto GO surface via pi-pi stacking to quench the fluorescent signal. T-Hg2+-T interaction was utilized to induce the catalytic self-assembly of hairpins with the aid of helper DNA. The formed rigid DNA triangles containing double strand DNA (dsDNA) was stiffer, and released from the surface of GO to cause a "turn-on" fluorescent signal. The limit of detection was 25 pM, which was comparable with those reported amplification strategies. This strategy showed good selectivity for Hg2+, and promising application for real samples. (C) 2017 Published by Elsevier B.V.
资助项目	National Natural Science Foundation of China[61307103] ; National Natural Science Foundation of China[81660658] ; Opening Project of Zhejiang Provincial Top Key Discipline of Pharmaceutical Sciences ; Open Research Fund Program of Key Laboratory of Reservoir Aquatic Environment of CAS ; [CQCM-2016-05]
WOS研究方向	Chemistry ; Electrochemistry ; Instruments & Instrumentation
语种	英语
出版者	ELSEVIER SCIENCE SA
WOS记录号	WOS:000403031500057
内容类型	期刊论文
源URL	[http://172.16.51.4:88/handle/2HOD01W0/152]
专题	太赫兹技术研究中心
通讯作者	Yun, Wen; Yang, Lizhu
作者单位	1.Chongqing Technol & Business Univ, Coll Environm & Resources, Chongqing Key Lab Catalysis & Funct Organ Mol, Chongqing 400067, Peoples R China 2.Wenzhou Med Univ, Sch Pharmaceut Sci, Wenzhou 325035, Zhejiang, Peoples R China 3.JiangXi Univ Tradit Chinese Med, Dept Pharm, Nanchang, Jiangxi, Peoples R China 4.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Key Lab Reservoir Aquat Environm CAS, Chongqing 400714, Peoples R China
推荐引用方式 GB/T 7714	Yun, Wen,Xiong, Wei,Wu, Hong,et al. Graphene oxide-based fluorescent "turn-on" strategy for Hg2+ detection by using catalytic hairpin assembly for amplification[J]. SENSORS AND ACTUATORS B-CHEMICAL,2017,249:493-498.
APA	Yun, Wen.,Xiong, Wei.,Wu, Hong.,Fu, Min.,Huang, Yu.,...&Yang, Lizhu.(2017).Graphene oxide-based fluorescent "turn-on" strategy for Hg2+ detection by using catalytic hairpin assembly for amplification.SENSORS AND ACTUATORS B-CHEMICAL,249,493-498.
MLA	Yun, Wen,et al."Graphene oxide-based fluorescent "turn-on" strategy for Hg2+ detection by using catalytic hairpin assembly for amplification".SENSORS AND ACTUATORS B-CHEMICAL 249(2017):493-498.