Novel cationic chitosan derivative bearing 1,2,3-triazolium and pyridinium: Synthesis, characterization, and antifungal property

doi:10.1016/j.carbpol.2017.11.023

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室 > 海岸带生物资源高效利用研究与发展中心

	Novel cationic chitosan derivative bearing 1,2,3-triazolium and pyridinium: Synthesis, characterization, and antifungal property
	Tan, Wenqiang 1,2; Li, Qing1 ; Dong, Fang1 ; Zhang, Jingjing 1,2; Luan, Fang 1,2; Wei, Lijie 1; Chen, Yuan 1,2; Guo, Zhanyong1,2 ; Guo, Zhanyong(Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China)
刊名	CARBOHYDRATE POLYMERS
	2018-02-15
卷号	182 页码:180-187
关键词	Chitosan Chemical Modification Click Chemistry Pyridinium 1 Antifungal Activity 2 3-triazolium
ISSN号	0144-8617
DOI	10.1016/j.carbpol.2017.11.023
产权排序	第1完成单位
文献子类	Article
英文摘要	In this paper, novel cationic chitosan derivative possessing 1,2,3-triazolium and pyridinium groups was synthesized conveniently via cuprous-catalyzed azide-alkyne cycloaddition (CuAAC) and methylation. FTIR, H-1 NMR, and elemental analysis examined the structural characteristics of the synthesized derivatives. The antifungal efficiencies of chitosan derivatives against three plant-threatening fungi were assayed by hypha measurement in vitro. The determination showed that chitosan derivative bearing 1,2,3-triazolium and pyridinium displayed tremendously enhanced antifungal activity as compared with chitosan and chitosan derivative bearing 1,2,3-triazole and pyridine. Notably, the inhibitory indices of it against Colletotrichum lagenarium attained 98% above at 1.0 mg/mL. The results showed that N-methylation of 1,2,3-triazole and pyridine could effectively enhance antifungal activity of the synthesized chitosan derivatives. Besides, the prepared chitosan derivatives showed non-toxic effect on cucumber seedlings. This synthetic strategy might provide an effective way and notion to prepare novel cationic chitosan antifungal biomaterials.
URL标识	查看原文
WOS关键词	QUATERNARY AMMONIUM CHITOSAN ; ENHANCED WATER-SOLUBILITY ; ANTIBACTERIAL ACTIVITY ; CLICK CHEMISTRY ; ANTIMICROBIAL ACTIVITIES ; BIOLOGICAL EVALUATION ; STARCH DERIVATIVES ; PATHOGENIC FUNGI ; IONIC LIQUID)S ; ANTIOXIDANT
WOS研究方向	Chemistry ; Polymer Science
语种	英语
WOS记录号	WOS:000418661800022
资助机构	National Natural Science Foundation of China(41576156) ; National Key Research and Development Program-China(2016YFF0202304) ; Shandong Province Science and Technology Development Plan(2015GSF121045) ; Yantai Science and Technology Development Plan(2015ZH078) ; Public Science and Technology Research Funds Projects of Ocean(201505022-3)
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/23551]
专题	海岸带生物资源高效利用研究与发展中心烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室烟台海岸带研究所_污染过程与控制实验室
通讯作者	Guo, Zhanyong; Guo, Zhanyong(Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China)
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Tan, Wenqiang,Li, Qing,Dong, Fang,et al. Novel cationic chitosan derivative bearing 1,2,3-triazolium and pyridinium: Synthesis, characterization, and antifungal property[J]. CARBOHYDRATE POLYMERS,2018,182:180-187.
APA	Tan, Wenqiang.,Li, Qing.,Dong, Fang.,Zhang, Jingjing.,Luan, Fang.,...&Guo, Zhanyong.(2018).Novel cationic chitosan derivative bearing 1,2,3-triazolium and pyridinium: Synthesis, characterization, and antifungal property.CARBOHYDRATE POLYMERS,182,180-187.
MLA	Tan, Wenqiang,et al."Novel cationic chitosan derivative bearing 1,2,3-triazolium and pyridinium: Synthesis, characterization, and antifungal property".CARBOHYDRATE POLYMERS 182(2018):180-187.