Differential and spatial regulation of the prophenoloxidase (proPO) and proPO-activating enzyme in cuticular melanization and innate immunity in Bombyx mori pupae

doi:10.1016/j.aspen.2015.09.007

CORC > 合肥物质科学研究院 > 中国科学院合肥物质科学研究院 > 中科院强磁场科学中心

	Differential and spatial regulation of the prophenoloxidase (proPO) and proPO-activating enzyme in cuticular melanization and innate immunity in Bombyx mori pupae
	Zou, Feng Ming 1,2; Lee, Kwang Sik 1; Kim, Bo Yeon 1; Kim, Hong Ja 3; Gui, Zhong Zheng 4; Zhang, Guo Zheng 4; Guo, Xijie 4; Jin, Byung Rae 1
刊名	JOURNAL OF ASIA-PACIFIC ENTOMOLOGY
	2015-12-01
卷号	18 期号:4 页码:757-764
关键词	Bombyx Mori Cuticular Melanization Development Innate Immunity Prophenoloxidase
DOI	10.1016/j.aspen.2015.09.007
文献子类	Article
英文摘要	Insect cuticular melanization is regulated by the prophenoloxidase (proPO)-activating system, which is also involved in the innate immune reaction. Here, we demonstrate how the differentiation of the proPO-activating system is regulated toward a cuticular melanization or innate immunity function in silkworm (Bombyx mori) pupae. Our results indicate that the differential and spatial regulation of key components, such as the proPO-activating enzyme and proPOs, primes the proPO-activating system for either cuticular melanization or innate immunity. This dual strategy for cuticular melanization in development and innate immunity upon infection demonstrates a two-pronged defense mechanism that is mediated by the priming of the proPO system. (C) 2015 Korean Society of Applied Entomology, Taiwan Entomological Society and Malaysian Plant Protection Society. Published by Elsevier B.V. All rights reserved.
WOS关键词	MANDUCA-SEXTA ; PHENOL OXIDASE ; SILKWORM ; PHENOLOXIDASE ; CLONING ; METAMORPHOSIS ; PURIFICATION ; HEMOCYTES ; CUTICLE ; SYSTEM
WOS研究方向	Entomology
语种	英语
WOS记录号	WOS:000369349600018
资助机构	Dong-A University Research Fund ; Dong-A University Research Fund ; Dong-A University Research Fund ; Dong-A University Research Fund ; Dong-A University Research Fund ; Dong-A University Research Fund ; Dong-A University Research Fund ; Dong-A University Research Fund ; Dong-A University Research Fund ; Dong-A University Research Fund ; Dong-A University Research Fund ; Dong-A University Research Fund ; Dong-A University Research Fund ; Dong-A University Research Fund ; Dong-A University Research Fund ; Dong-A University Research Fund
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/22281]
专题	合肥物质科学研究院_中科院强磁场科学中心
作者单位	1.Dong A Univ, Coll Nat Resources & Life Sci, Busan 604714, South Korea 2.Chinese Acad Sci, High Field Magnet Lab, Hefei 230031, Anhui, Peoples R China 3.Gyeongsang Natl Univ, Div Appl Life Sci, Jinju, South Korea 4.Chinese Acad Agr Sci, Sericultural Res Inst, Zhenjiang, Peoples R China
推荐引用方式 GB/T 7714	Zou, Feng Ming,Lee, Kwang Sik,Kim, Bo Yeon,et al. Differential and spatial regulation of the prophenoloxidase (proPO) and proPO-activating enzyme in cuticular melanization and innate immunity in Bombyx mori pupae[J]. JOURNAL OF ASIA-PACIFIC ENTOMOLOGY,2015,18(4):757-764.
APA	Zou, Feng Ming.,Lee, Kwang Sik.,Kim, Bo Yeon.,Kim, Hong Ja.,Gui, Zhong Zheng.,...&Jin, Byung Rae.(2015).Differential and spatial regulation of the prophenoloxidase (proPO) and proPO-activating enzyme in cuticular melanization and innate immunity in Bombyx mori pupae.JOURNAL OF ASIA-PACIFIC ENTOMOLOGY,18(4),757-764.
MLA	Zou, Feng Ming,et al."Differential and spatial regulation of the prophenoloxidase (proPO) and proPO-activating enzyme in cuticular melanization and innate immunity in Bombyx mori pupae".JOURNAL OF ASIA-PACIFIC ENTOMOLOGY 18.4(2015):757-764.