Enantiomeric Catalytic Formal Thiolation of 2,5-Dimethyl-3-[1-(arylsulfonyl)alkyl]pyrroles in an Oil/Water Biphasic System

	Enantiomeric Catalytic Formal Thiolation of 2,5-Dimethyl-3-[1-(arylsulfonyl)alkyl]pyrroles in an Oil/Water Biphasic System
	Chen, Ping 1,2; Yang, Qin 1; Lu, Shengmei 1; Li, Can 1; Wang, Peng 1; Liu, Yan 1
刊名	EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
	2016-12-01
期号	35 页码:5826-5830
关键词	Asymmetric synthesis Conjugate addition Enantioselectivity Nitrogen heterocycles Organocatalysis
英文摘要	The asymmetric synthesis of 3-sec-substituted pyrrole derivatives through vinylogous imine intermediates generated in situ from 2,5-dimethyl-3-[1-(arylsulfonyl)alkyl]pyrroles with high activity and enantioselectivity (up to 98% ee) was examined. Employing a cinchona alkaloid based chiral bifunctional organocatalyst, the reaction of tritylthiol to sulfonylpyrroles delivered a series of highly enantioselective sulfur-containing 3-sec-substituted pyrroles.
WOS标题词	Science & Technology ; Physical Sciences
类目[WOS]	Chemistry, Organic
研究领域[WOS]	Chemistry
关键词[WOS]	BETA-SUBSTITUTED TRYPTOPHANS ; ASYMMETRIC MICHAEL ADDITION ; DIELS-ALDER REACTIONS ; GENERATED IN-SITU ; ANTIMALARIAL ACTIVITY ; ENANTIOSELECTIVE SYNTHESIS ; CONJUGATE ADDITION ; EMULSION DROPLETS ; CYCLOPRODIGIOSIN HYDROCHLORIDE ; ABSOLUTE-CONFIGURATION
收录类别	SCI
语种	英语
WOS记录号	WOS:000390780000008
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/150509]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Catalysis, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Chen, Ping,Yang, Qin,Lu, Shengmei,et al. Enantiomeric Catalytic Formal Thiolation of 2,5-Dimethyl-3-[1-(arylsulfonyl)alkyl]pyrroles in an Oil/Water Biphasic System[J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY,2016(35):5826-5830.
APA	Chen, Ping,Yang, Qin,Lu, Shengmei,Li, Can,Wang, Peng,&Liu, Yan.(2016).Enantiomeric Catalytic Formal Thiolation of 2,5-Dimethyl-3-[1-(arylsulfonyl)alkyl]pyrroles in an Oil/Water Biphasic System.EUROPEAN JOURNAL OF ORGANIC CHEMISTRY(35),5826-5830.
MLA	Chen, Ping,et al."Enantiomeric Catalytic Formal Thiolation of 2,5-Dimethyl-3-[1-(arylsulfonyl)alkyl]pyrroles in an Oil/Water Biphasic System".EUROPEAN JOURNAL OF ORGANIC CHEMISTRY .35(2016):5826-5830.