Extracorporeally frozen tumour-bearing bone combined with free vascularised fibula for the intercalary reconstruction of femoral defect after resection of bony sarcoma

doi:10.1016/j.bjps.2016.02.018

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	Extracorporeally frozen tumour-bearing bone combined with free vascularised fibula for the intercalary reconstruction of femoral defect after resection of bony sarcoma
	Li, J; Zhang, FJ; Yang, M; Liu, SP; Wang, X; Yang, QZ; Wu, ZG; Ji, CL; Li, J (reprint author), Xijing Hosp, Dept Orthopaed, Xian 710032, Peoples R China.
刊名	JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
	2016-06
卷号	69 期号:6 页码:856-863
关键词	Sarcoma Femur Frozen autograft Reconstruction Fibula flap
ISSN号	1748-6815
DOI	10.1016/j.bjps.2016.02.018
文献子类	Article
英文摘要	Background: With the improved survival for patients with bone sarcomas, there is a trend to reconstruct intercalary femur defects using biologic techniques. This study examined whether the results of a frozen femur autograft with vascularised fibula are comparable to other reconstructive options in terms of the functional outcomes and the complications. Materials and methods: Between 2008 and 2012, eight patients with bony sarcoma of the femur were subjected to reconstruction with a recycled frozen autograft combined with a vascularised fibula flap inside. The oncologic and functional results were analysed retrospectively. Results: The mean follow-up was 48.7 months (37-71). The oncologic results were continuously disease free in five patients; there was no evidence of disease in one, one patient was alive with disease and another died of the disease. The average length of defect was 13.6 cm (9-21). Bone union was achieved in all cases. The mean time to bone union was 7.9 months (5-19) and to full weight bearing was 7.8 months (6-11). There was no infection or construct fracture in this series. Two complications were observed. One tumour recurrence in soft tissue was treated with reresection. One tibia fracture was successfully managed with cast immobilisation. The average Musculoskeletal Tumor Society functional score was 95% (27-30). The construct was intact in all patients. Conclusions: Vascularised fibular flap combined with frozen autografts is a dependable and durable option for the reconstruction of large bony defects after femoral sarcoma resection. It had the merits of reliable bone union and low complications, which compare well with other biological reconstructions. Evidence Rating Scale for Therapeutic Studies Level IV, therapeutic study. (C) 2016 Published by Elsevier Ltd on behalf of British Association of Plastic, Reconstructive and Aesthetic Surgeons.
学科主题	Surgery
出版地	OXFORD
语种	英语
WOS记录号	WOS:000377412500020
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/178496]
专题	学院待认领_期刊论文
通讯作者	Li, J (reprint author), Xijing Hosp, Dept Orthopaed, Xian 710032, Peoples R China.
推荐引用方式 GB/T 7714	Li, J,Zhang, FJ,Yang, M,et al. Extracorporeally frozen tumour-bearing bone combined with free vascularised fibula for the intercalary reconstruction of femoral defect after resection of bony sarcoma[J]. JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY,2016,69(6):856-863.
APA	Li, J.,Zhang, FJ.,Yang, M.,Liu, SP.,Wang, X.,...&Li, J .(2016).Extracorporeally frozen tumour-bearing bone combined with free vascularised fibula for the intercalary reconstruction of femoral defect after resection of bony sarcoma.JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY,69(6),856-863.
MLA	Li, J,et al."Extracorporeally frozen tumour-bearing bone combined with free vascularised fibula for the intercalary reconstruction of femoral defect after resection of bony sarcoma".JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY 69.6(2016):856-863.