Relationship between coronal intercondylar notch width index and osteoarthritis

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	Relationship between coronal intercondylar notch width index and osteoarthritis
	Chen, Cong; Ma, Yin-Hua; Tan, Xiao-Yi; Zhang, Bo; Geng, Bin; Jiang, Jin; Wu, Meng; Xia, Ya-Yi
刊名	Nan fang yi ke da xue xue bao = Journal of Southern Medical University
	2015-10
卷号	35 期号:10 页码:1384-1389
关键词	骨性关节炎髁间窝狭窄髁间窝宽度指数髁间窝形状核磁共振
ISSN号	1673-4254
其他题名	冠状位髁间窝宽度指数与骨关节炎的关系
文献子类	Article
英文摘要	OBJECTIVE: To study the relationship between knee osteoarthritis (OA) and intercondylar notch narrowing based on the notch width index.METHODS: Magnetic resonance (MR) images were collected from middle-aged and elderly patients with a definite diagnosis of knee OA, including 42 with mild OA and 37 with moderate to severe OA, with 70 healthy individuals serving as the control group. The notch width indexes NWI, NWI-A, and NWI-P on the coronal images at different levels were calculated, and the intercondylar notch was classified, according to the features on axial MR images, into types A, U, and W. The association of OA with NWI, NWI-A, NWI-P, and notch type was determined, and the cutoff values were obtained based on the ROC curves at different levels as indicators for diagnosis of intercondylar notch stenosis.RESULTS: In the control, mild OA, moderate to severe OA groups, the NWI value on coronal MR images were 0.252±0.019, 0.251±0.017, and 0.240±0.020, NWI-A were 0.261±0.024, 0.259±0.023, and 0.245±0.023, and NWI-P were 0.271±0.026, 0.270±0.024, and 0.254±0.022, respectively. Patients with moderate to severe OA had significantly smaller NWI, NWI-A, and NWI-P than the other two groups (P<0.05), and a significant association was found between NWI values at each level and the occurrence of moderate to severe OA (P<0.01). A NWI value<0.248, NWI-A<0.256, and NWI-P<0.266 supported a diagnosis of intercondylar notch narrowing. Type A intercondylar notch was found in the majority of patients with intercondylar notch narrowing (P<0.05).CONCLUSION: Patients with moderate to severe OA have significant intercondylar notch narrowing, and patients with a type A intercondylar notch are more likely to have intercondylar notch narrowing than those with type U notch.
学科主题	Geriatrics & Gerontology ; Pathology ; Anatomy & Morphology ; Radiology, Nuclear Medicine & Medical Imaging ; Rheumatology ; Mathematics (Provided By Thomson Reuters)
资助项目	国家自然科学基金项目 ; 甘肃省青年科技基金计划 ; 兰州市科技局资助项目
项目编号	国家自然科学基金 ; 甘肃省青年科技研究基金 ; 兰州市科技发展计划项目
语种	中文
CSCD记录号	CSCD:5555777
资助机构	NSFC ; GSSTD ; LZSTB
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/179397]
专题	第二临床医学院_期刊论文
推荐引用方式 GB/T 7714	Chen, Cong,Ma, Yin-Hua,Tan, Xiao-Yi,et al. Relationship between coronal intercondylar notch width index and osteoarthritis[J]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University,2015,35(10):1384-1389.
APA	Chen, Cong.,Ma, Yin-Hua.,Tan, Xiao-Yi.,Zhang, Bo.,Geng, Bin.,...&Xia, Ya-Yi.(2015).Relationship between coronal intercondylar notch width index and osteoarthritis.Nan fang yi ke da xue xue bao = Journal of Southern Medical University,35(10),1384-1389.
MLA	Chen, Cong,et al."Relationship between coronal intercondylar notch width index and osteoarthritis".Nan fang yi ke da xue xue bao = Journal of Southern Medical University 35.10(2015):1384-1389.