Size- and shape-dependent peroxidase-like catalytic activity of MnFe2O4 Nanoparticles and their applications in highly efficient colorimetric detection of target cancer cells

doi:10.1039/c5dt01585e

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	Size- and shape-dependent peroxidase-like catalytic activity of MnFe2O4 Nanoparticles and their applications in highly efficient colorimetric detection of target cancer cells
	Peng, YH; Wang, ZY; Liu, WS; Zhang, HL; Zuo, W; Tang, HA; Chen, FJ; Wang, BD; Wang, BD (reprint author), Lanzhou Univ Gansu, Key Lab Nonferrous Met Chem & Resources Utilizat, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China.
刊名	DALTON TRANSACTIONS
	2015
卷号	44 期号:28 页码:12871-12877
ISSN号	1477-9226
DOI	10.1039/c5dt01585e
其他题名	Size- and shape-dependent peroxidase-like catalytic activity of MnFe2O4Nanoparticles and their applications in highly efficient colorimetric detection of target cancer cells
文献子类	Article
英文摘要	The catalytic activity of nanocrystal catalysts depends strongly on their chemical composition, size, and shape. Herein, we report four different sizes and shapes of MnFe2O4 nanoparticles (NPs) prepared by a hydrothermal procedure. In addition, the size- and shape-dependent peroxidase-like activity of these NPs was first explored using 3,3', 5,5'-tetramethyl-benzidine and H2O2 as peroxidase substrates. The results showed that the peroxidase-like activities of the MnFe2O4 NPs were size- and shape-dependent and followed the order of 4 nm (spherical) > 18 nm (plate-like) > 27 nm (near-cubic) > 16 nm (spherical); this order was closely related to their surface-to-volume ratio and atom arrangements. Such an investigation is of great significance for peroxidase nanomimetics with enhanced activity and utilization. Furthermore, folic acid (FA)-conjugated MnFe2O4 NPs allow the detection of folate receptor-rich cancer cells. Such investigation can be widely utilized for the identification of important target molecules.
学科主题	Chemistry
出版地	CAMBRIDGE
资助项目	国家自然科学基金项目 ; 国家重点基础研究发展计划以及国家重大科学研究计划（973计划） ; 新世纪优秀人才支持计划 ; 中央高校基本科研业务费专项资金
项目编号	National Natural Science Foundation of China [21271093, 21431002, 21401091] ; National Basic Research Program of China (973 Program) [2012CB933102] ; Program for New Century Excellent Talents in University [NCET-13-0262] ; Fundamental Research Funds for the Central Universities [lzujbky-2014-k06] ; education research project of Gansu Province [2013A-102] ; planning project of Chengguan District in Lanzhou [2013-4-1]
语种	英语
WOS记录号	WOS:000357899600051
资助机构	NSFC ; MOST ; MOE ; LZU
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/179306]
专题	第二临床医学院_期刊论文
通讯作者	Wang, BD (reprint author), Lanzhou Univ Gansu, Key Lab Nonferrous Met Chem & Resources Utilizat, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China.
推荐引用方式 GB/T 7714	Peng, YH,Wang, ZY,Liu, WS,et al. Size- and shape-dependent peroxidase-like catalytic activity of MnFe2O4 Nanoparticles and their applications in highly efficient colorimetric detection of target cancer cells[J]. DALTON TRANSACTIONS,2015,44(28):12871-12877.
APA	Peng, YH.,Wang, ZY.,Liu, WS.,Zhang, HL.,Zuo, W.,...&Wang, BD .(2015).Size- and shape-dependent peroxidase-like catalytic activity of MnFe2O4 Nanoparticles and their applications in highly efficient colorimetric detection of target cancer cells.DALTON TRANSACTIONS,44(28),12871-12877.
MLA	Peng, YH,et al."Size- and shape-dependent peroxidase-like catalytic activity of MnFe2O4 Nanoparticles and their applications in highly efficient colorimetric detection of target cancer cells".DALTON TRANSACTIONS 44.28(2015):12871-12877.