Preparation and Characterization of Chitosan-Casein Phosphopeptides Biocomposite Coatings on the Medical Titanium Alloy

doi:10.4028/www.scientific.net/KEM.480-481.1065

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	Preparation and Characterization of Chitosan-Casein Phosphopeptides Biocomposite Coatings on the Medical Titanium Alloy
	Liu, B; Wang, L; Bu, YZ; Yang, SR; Wang, JQ; Liu, B (reprint author), Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Peoples R China.
	2011
会议日期	MAY 05-06, 2011
会议地点	Singapore, SINGAPORE
关键词	Titanium alloy Chitosan Casein phosphopeptides Composite coatings
卷号	480-481
DOI	10.4028/www.scientific.net/KEM.480-481.1065
页码	1065-1069
英文摘要	Titanium (Ti) and its alloys have been applied in orthopedics as one of the most popular biomedical metallic implant materials. In this work, to enhance the bioactivity, the surface of Ti alloy pre-modified by silane coupling agent and glutaraldehyde was covalently grafted with chitosan (CS) via biochemical multistep self-assembled method. Then, for the first time, the achieved surface was further immobilized with casein phosphopeptides (CPP), which are one group of bioactive peptides released from caseins in the digestive tract and can facilitate the calcium adsorption and usage, to form CS-CPP biocomposite coatings. The structure and composition of the fabricated coatings were characterized by X-ray photoelectron spectroscopy (XPS), attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and atomic force microscopy (AFM). As the experimental results indicated, multi-step assembly was successfully performed, and the CS and CPP were assembled onto the Ti alloy surface orderly. It is anticipated that the Ti alloys modified by CS-CPP biocomposite coatings will find potential applications as implant materials in biomedical fields.
会议录	MATERIALS ENGINEERING FOR ADVANCED TECHNOLOGIES, PTS 1 AND 2
会议录出版地	STAFA-ZURICH
学科主题	Materials Science
语种	英语
ISSN号	1013-9826
WOS记录号	WOS:000309483200199
内容类型	会议论文
源URL	[http://ir.lzu.edu.cn/handle/262010/185251]
专题	口腔医学院_会议论文
通讯作者	Liu, B (reprint author), Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Peoples R China.
推荐引用方式 GB/T 7714	Liu, B,Wang, L,Bu, YZ,et al. Preparation and Characterization of Chitosan-Casein Phosphopeptides Biocomposite Coatings on the Medical Titanium Alloy[C]. 见:. Singapore, SINGAPORE. MAY 05-06, 2011.