A Critical Review of the Quality of Cough Clinical Practice Guidelines

doi:10.1016/j.chest.2016.04.028

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	A Critical Review of the Quality of Cough Clinical Practice Guidelines
	Jiang, M; Guan, WJ; Fang, ZF; Xie, YQ; Xie, JX; Chen, H; Wei, D; Lai, KF; Zhong, NS; Lai, KF (reprint author), Guangzhou Med Univ, Guangzhou Inst Resp Dis, Natl Clin Res Ctr Resp Dis, Affiliated Hosp 1,State Key Lab Resp Dis, 151 Yanjiang Rd, Guangzhou, Guangdong, Peoples R China.
刊名	CHEST
	2016-10
卷号	150 期号:4 页码:777-788
关键词	AGREE instrument clinical practice guidelines cough
ISSN号	0012-3692
DOI	10.1016/j.chest.2016.04.028
文献子类	Review
英文摘要	BACKGROUND: Clinical practice guidelines (CPGs) have been developed to provide health-care practitioners with the best possible evidence, but the quality of these CPGs varies greatly. OBJECTIVE: The goal of this study was to systematically evaluate the quality of cough CPGs and identify gaps limiting evidence-based practice. METHODS: Systematic searches were conducted to identify cough CPGs in guideline databases, developers' Websites, and Medline. Four reviewers independently evaluated eligible guidelines by using the Appraisal of Guidelines for Research and Evaluation II assessment tool. Agreement among reviewers was measured by using the intraclass correlation coefficient. The number of recommendations, strength of recommendation, and levels of evidence were determined. RESULTS: Fifteen cough CPGs were identified. An overall high degree of agreement among reviewers was observed (intraclass correlation coefficient, 0.82 [95% CI, 0.79-0.85]). The quality ranged from good to acceptable in the scope and purpose (mean, 72%; range, 54%93%) and clarity and presentation (mean, 68%; range, 50%-90%) domains but not in stakeholder involvement (mean, 36%; range, 18%-90%), rigor of development (mean, 36%; range, 9%-93%), applicability (mean, 23%; range, 9%-83%), and editorial independence domains (mean, 24%; range, 0-96%). Seven guidelines (46.7%) were considered "strongly recommended" or "recommended with modifications" for clinical practice. More than 70% of recommendations were based on nonrandomized studies (Level C, 30.4%) and expert opinion (Level D, 41.3%). CONCLUSIONS: The quality of cough CPGs is variable, and recommendations are largely based on low-quality evidence. There is significant room for improvement to develop high-quality guidelines, which urgently warrants first-class research to minimize the vital gaps in the evidence for formulation of cough CPGs.
学科主题	General & Internal Medicine ; Respiratory System
出版地	GLENVIEW
资助项目	国家自然科学基金项目
项目编号	National Natural Science Foundation of China [81402772]
语种	英语
WOS记录号	WOS:000384772800012
资助机构	NSFC
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/188720]
专题	基础医学院_期刊论文
通讯作者	Lai, KF (reprint author), Guangzhou Med Univ, Guangzhou Inst Resp Dis, Natl Clin Res Ctr Resp Dis, Affiliated Hosp 1,State Key Lab Resp Dis, 151 Yanjiang Rd, Guangzhou, Guangdong, Peoples R China.
推荐引用方式 GB/T 7714	Jiang, M,Guan, WJ,Fang, ZF,et al. A Critical Review of the Quality of Cough Clinical Practice Guidelines[J]. CHEST,2016,150(4):777-788.
APA	Jiang, M.,Guan, WJ.,Fang, ZF.,Xie, YQ.,Xie, JX.,...&Lai, KF .(2016).A Critical Review of the Quality of Cough Clinical Practice Guidelines.CHEST,150(4),777-788.
MLA	Jiang, M,et al."A Critical Review of the Quality of Cough Clinical Practice Guidelines".CHEST 150.4(2016):777-788.