The quality of evidence in Chinese meta-analyses needs to be improved

doi:10.1016/j.jclinepi.2016.01.003

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	The quality of evidence in Chinese meta-analyses needs to be improved
	Yao, L; Sun, R; Chen, YL; Wang, Q; Wei, D; Wang, XQ; Yang, KH; Yang, KH (reprint author), Lanzhou Univ, Sch Basic Med Sci, Evidence Based Med Ctr, 199 Donggang Rd, Lanzhou, Peoples R China.
刊名	JOURNAL OF CLINICAL EPIDEMIOLOGY
	2016-06
卷号	74 页码:73-79
关键词	GRADE Meta-analysis (MA) Quality of evidence Traditional Chinese medicine (TCM) Systematic review TCM review Cochrane review
ISSN号	0895-4356
DOI	10.1016/j.jclinepi.2016.01.003
文献子类	Review
英文摘要	Objectives: We conducted a systematic review using GRADE (Grading of Recommendations Assessment, Development and Evaluation) system to assess the quality of evidence of Chinese meta-analyses (MAs). Design/Setting: A systematic review of MAs listed in Chinese Biomedicine Literature Database from January 2010 to December 2012. Methods: Mesh term "meta-analysis" was used to search the Chinese Biomedicine Literature Database from January 2010 to December 2012. Characteristics and main outcomes of each included MA were extracted, and the GRADE system was used to assess the quality of evidence for each outcome. A 10% random sample of Cochrane MAs between 2010 and 2012 was also assessed as control group. Results: A total of 564 Chinese MAs (including 1,237 main outcomes) and 95 Cochrane MAs (including 251 main outcomes) were identified. Almost half (600, 48.5%) of the outcomes in Chinese MAs were rated as low, and the proportion of outcomes with high or moderate quality of evidence was lower in Chinese MAs than Cochrane MAs (Chinese, 406 [32.8%] vs. Cochrane MAs, 155 [61.8%], P < 0.001). Of the outcomes in Chinese MAs, 1,012 (81.8%) were downgraded for risk of bias. Other common factors for downgrading were imprecision (448, 36.2%), publication bias (418, 33.8%), inconsistency (351, 28.4%), and indirectness (1, 0.1%). Conclusions: Chinese MAs were of low quality of evidence. Risk of bias, inconsistency, and publication bias were the three most common downgrade factors in Chinese MAs. Efforts must be made to improve quality of evidence of Chinese MAs, and a call for more rigorous training of investigators in China is warranted. (C) 2016 Elsevier Inc. All rights reserved.
学科主题	Health Care Sciences & Services ; Public, Environmental & Occupational Health
出版地	NEW YORK
语种	英语
WOS记录号	WOS:000379452300010
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/179121]
专题	基础医学院_期刊论文
通讯作者	Yang, KH (reprint author), Lanzhou Univ, Sch Basic Med Sci, Evidence Based Med Ctr, 199 Donggang Rd, Lanzhou, Peoples R China.
推荐引用方式 GB/T 7714	Yao, L,Sun, R,Chen, YL,et al. The quality of evidence in Chinese meta-analyses needs to be improved[J]. JOURNAL OF CLINICAL EPIDEMIOLOGY,2016,74:73-79.
APA	Yao, L.,Sun, R.,Chen, YL.,Wang, Q.,Wei, D.,...&Yang, KH .(2016).The quality of evidence in Chinese meta-analyses needs to be improved.JOURNAL OF CLINICAL EPIDEMIOLOGY,74,73-79.
MLA	Yao, L,et al."The quality of evidence in Chinese meta-analyses needs to be improved".JOURNAL OF CLINICAL EPIDEMIOLOGY 74(2016):73-79.